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119-24-4

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Product FOB Price Min.Order Supply Ability Supplier
PTEROIC ACID
Cas No: 119-24-4
USD $ 2.0-2.0 / Metric Ton 1 Metric Ton 1 Metric Ton/Week GIHI CHEMICALS CO.,LIMITED Contact Supplier
Pteroic acid
Cas No: 119-24-4
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Pteroic acid
Cas No: 119-24-4
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic acid
Cas No: 119-24-4
USD $ 1.0-1.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Enke Pharma-tech Co.,Ltd. (Cangzhou, China ) Contact Supplier
Pteroic acid
Cas No: 119-24-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Cheap NSC 14972 99% 50KG in stock
Cas No: 119-24-4
No Data 1 Gram Metric Ton/Day Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd Contact Supplier
PTEROIC ACID
Cas No: 119-24-4
USD $ 0.9-1.0 / Kilogram 1 Kilogram 1000 Kilogram/Month LIDE PHARMACEUTICALS LIMITED Contact Supplier
high quality 119-24-4 PTEROIC ACID with best price
Cas No: 119-24-4
No Data 10 Gram 1000 Metric Ton/Month Hubei XinRunde Chemical Co., Ltd Contact Supplier
high quality119-24-4 PTEROIC ACID with best price
Cas No: 119-24-4
USD $ 1.0-2.0 / Gram 10 Gram 12 Kilogram/Day Hubei Jusheng Technology Co., Ltd., Contact Supplier
TIANFU-CHEM - PTEROIC ACID
Cas No: 119-24-4
USD $ 1000.0-1000.0 / Kilogram 1 Kilogram 10 Metric Ton/Month Henan Tianfu Chemical Co., Ltd. Contact Supplier

119-24-4 Usage

Enzyme inhibitor

This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.

Purification Methods

Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]

Uses

Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.
InChI:InChI=1/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)

119-24-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma-Aldrich (Y0001243)  Folic acid impurity D  European Pharmacopoeia (EP) Reference Standard 119-24-4 Y0001243 1,880.19CNY Detail
Aldrich (P1781)  Pteroicacid  ≥93% 119-24-4 P1781-25MG 741.78CNY Detail
Aldrich (P1781)  Pteroicacid  ≥93% 119-24-4 P1781-50MG 1,289.34CNY Detail
Aldrich (P1781)  Pteroicacid  ≥93% 119-24-4 P1781-100MG 2,237.04CNY Detail

119-24-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid

1.2 Other means of identification

Product number -
Other names Pteroic Acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119-24-4 SDS

119-24-4Downstream Products

119-24-4Related news

Determination of PTEROIC ACID (cas 119-24-4) by high-performance thin-layer chromatography: Contribution to the investigation of 7,8-dihydropteroate synthase09/03/2019

A TLC method was developed that allows the evaluation of the 7,8-dihydropteroate synthase reaction via determination of the stable pteroic acid (PtA), obtained by chemical oxidation of the enzymatic product dihydropteroic acid (H2PtA). Using amino-bonded HPTLC plates and solution of 52% acetonit...detailed

Preparation and purification of PTEROIC ACID (cas 119-24-4) from folic acid09/02/2019

Crude pteroic acid, obtained by microbiological degradation of folic acid, has been purified by column chromatography on cellulose CF11, eluting with 0.1 M glycine buffer of pH 10.0, containing 0.15% w/v ascorbic acid and saturated with isoamyl alcohol.detailed

[92] Preparation and purification of PTEROIC ACID (cas 119-24-4) from pteroylglutamic acid (folic acid)09/01/2019

Publisher SummaryThis chapter describes the preparation and purification of pteroic acid from pteroylglutamic acid (folic acid). Pteroic acid can be prepared conveniently, by the removal of glutamic acid, from commercially available pteroyiglutamic acid, using a pteroylglutamic acid-degrading ps...detailed

Pharmaceutical NanotechnologyEnhanced cellular delivery of idarubicin by surface modification of propyl starch nanoparticles employing PTEROIC ACID (cas 119-24-4) conjugated polyvinyl alcohol08/30/2019

Enhanced intracellular internalization of the anti-cancer active idarubicin (IDA) was achieved through appropriate surface modification of IDA loaded propyl starch nanoparticles. This was conducted by synthesizing pteroic acid modified polyvinyl alcohol (ptPVA) and employing this stabilizer for ...detailed

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