29207-86-1

Upstream product

• 29207-85-0 N'-[chloro-(4-chloro-phenyl)-methylene]-morpholine-4-carbohydrazonoyl chloride 
• 29091-85-8 4-chloro-N'-dichloromethylene-benzohydrazonoyl chloride 
• 23328-69-0 4-chloromorpholine 
• 23289-10-3 2-(4-chlorophenyl)-1,3,4-oxadiazole 
• 5765-65-1 4-(benzoyloxy)morpholine 
• 26037-18-3 morpholine-4-carboxylic acid (4-chloro-benzylidene)-hydrazide 

Relevant academic research and scientific papers

Functionalization of 1,3,4-Oxadiazoles and 1,2,4-Triazoles via Selective Zincation or Magnesiation Using 2,2,6,6-Tetramethylpiperidyl Bases

We report the metalation of the 1,3,4-oxadiazole and 1,2,4-triazole scaffolds via regioselective zincation or magnesiation using the TMP bases (TMP = 2,2,6,6-tetramethylpiperidyl) TMP2Zn·2LiCl, TMP2Zn·2MgCl2·2LiCl, TMPMgCl

A new entry of amination reagents for heteroaromatic C-H bonds: Copper-catalyzed direct amination of azoles with chloroamines at room temperature

Chloroamine serves as an efficient amination reagent to the heteroaromatic C-H bond of azole under copper catalysis even at room temperature. This catalysis enables a rapid and concise construction of aminoazoles of great interest in biological and medicinal chemistry.