29209-75-4

Upstream product

• 16348-49-5 2-amino-N’-hydroxybenzimidamide 
• 555-16-8 4-nitrobenzaldehdye 
• 29083-68-9 3-oxy-2-propyl-1,2-dihydro-quinazolin-4-ylamine 
• 1885-29-6 anthranilic acid nitrile 
• 108732-43-0 2-Methyl-3-oxy-1,2-dihydro-quinazolin-4-ylamine 

Relevant academic research and scientific papers

Substrate-Independent High-Throughput Assay for the Quantification of Aldehydes

The selective and direct reduction of carboxylic acids into the corresponding aldehydes by chemical methods is still a challenging task in synthesis. Several reductive and oxidative chemical methods are known to produce aldehydes, but most of them require

A New type of Dimroth Rearrangement: Formation of 1,2-Dihydro-3H-quinazolone 4-Oximes from 4-Amino-1,2-dihydroquinazoline 3-Oxides

Contrary to earlier claims the primary product of the reaction of aldehydes and o-aminobenzamide oxime is, irrespective of the aldehyde, always a 4-amino-1,2-dihydroquinazoline 3-oxide.Thermolysis of 1-unsubstituted 2-substituted quinazoline 3-oxides (5) in solution or in melt gives rise, by a new type of Dimroth rearrangement, to the isomeric 1,2-dihydro-4-quinazolone oximes (6), while the 1-benzyl 2-unsubstituted analogue (9j) yields, presumably by an addition-elimination ring transformation coupled with oxidation, a quinoidal quinazolone 4-oxime (17).