292166-97-3

Upstream product

• 20834-61-1 2-bromo-4,6-di-tert-butylphenol 
• 75-03-6 ethyl iodide 
• 96-76-4 2,4-di-tert-Butylphenol 

Downstream Products

• 292166-99-5 1,5-di-tert-butyl-2-ethoxy-3-ethynyl-benzene 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER

The disclosure relates to rexinoids, including compounds of the Formula (I) and (II) or a pharmaceutically acceptable salt, polymorph, prodrug, solvate or clathrate thereof. These rexinoids are useful for increasing PD-L1 in vivo, for treatment of cancer, and for inhibiting the onset of cancer.

RETINOID ANTAGONISTS AND USE THEREOF

The present invention relates to novel retinoid antagonists of the formula (I) wherein the dotted bond is optional; and, when the dotted bond is present, R is lower alkyl and R is hydrogen; and, when the dotted bond is absent, R and R taken to

Retinoid antagonists and use thereof

The present invention relates to novel retinoid antagonists of the formula I wherein the dotted bond can be either hydrogenated or form a double bond; and, when the dotted bond forms a double bond, R1is lower alkyl and R2is hydrogen;