2923-73-1 Usage
General Description
2'-Fluorothymidine is a synthetic organic compound that is derived from thymidine, a nucleoside involved in DNA replication and repair. This chemical is commonly used as a radiotracer in positron emission tomography (PET) imaging to visualize and track cellular proliferation in cancerous tissues. Its fluorinated structure, particularly the substitution of a hydrogen with a fluorine atom at the 2' position, enhances its resistance to rapid degradation by enzymes, thereby increasing its stability and prolonging its presence in the body for imaging purposes. Additionally, 2'-fluorothymidine has shown promise in the development of new cancer therapies and treatments, as it is able to target and inhibit the growth of rapidly dividing cancer cells, making it a valuable tool in both diagnostic and therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 2923-73-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,2 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2923-73:
(6*2)+(5*9)+(4*2)+(3*3)+(2*7)+(1*3)=91
91 % 10 = 1
So 2923-73-1 is a valid CAS Registry Number.
2923-73-1Relevant articles and documents
S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS
-
, (2021/06/22)
Various embodiments provide STOPS? polymers that are S-antigen transport inhibiting oligonucleotide polymers, processes for making them and methods of using them to treat diseases and conditions. In some embodiments the STOPS? modified oligonucleotides include an at least partially phosphorothioated sequence of alternating A and C units having modifications as described herein. The sequence independent antiviral activity against hepatitis B of embodiments of STOPS? modified oligonucleotides, as determined by HBsAg Secretion Assay, is an EC50 that is less than 100 nM.
MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
-
Page/Page column 95, (2020/05/15)
The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside.
Green synthetic process of clevudine
-
Paragraph 0029; 0030; 0031; 0033, (2019/03/29)
The invention relates to a green synthetic process of clevudine. The green synthetic process comprises the following steps: dissolving a compound II as shown in the description in an organic solvent,adding 40% hydrobromic acid and tetrabutylammonium fluor
