292617-20-0Relevant articles and documents
Synthesis and activity of fluorinated derivatives of sulindac sulphide and sulindac sulphone
Jung, Manfred,Wahl, Alan F.,Neupert, Werner,Geisslinger, Gerd,Senter, Peter D.
, p. 217 - 221 (2007/10/03)
The synthesis of fluorinated derivatives of the sulphide and sulphone metabolites of sulindac, a non-steroidal anti-inflammatory agent with chemopreventative activity, is reported. The key step in the synthesis is a Pummerer-rearrangement of the parent su