292620-20-3

Basic information

• Product Name: L-Phenylalaninamide, N-[(2R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-1,4-dioxo-6-phenyl- 2-(phenylmethyl)hexyl]-L-leucyl-
• CAS NO: 292620-20-3
• Molecular Formula: C39H50N4O6
• Molecular Weight: 670.849
• Mol File: 292620-20-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Phenylalaninamide, N-[(2R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-1,4-dioxo-6-phenyl- 2-(phenylmethyl)hexyl]-L-leucyl-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalaninamide, N-[(2R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-1,4-dioxo-6-phenyl- 2-(phenylmethyl)hexyl]-L-leucyl-(292620-20-3)
• EPA Substance Registry System: L-Phenylalaninamide, N-[(2R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-1,4-dioxo-6-phenyl- 2-(phenylmethyl)hexyl]-L-leucyl-(292620-20-3)

Safety Data

• Hazardous Substances Data: 292620-20-3(Hazardous Substances Data)

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 33900-15-1 (2S)-N-[(1S)-2-amino-1-benzyl-2-oxoethyl]-2-[(tert-butoxycarbonyl)amino]-4-methylpentanamide 
• 88463-18-7 (S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropionamide 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 5241-58-7 L-Phenylalanine amide 
• 126409-24-3 {(1S)-benzyl-(4R)-[1-((1S)-carbamoyl-2-phenyl-ethylcarbamoyl)-(1S)-3-methyl-butyl-carbamoyl]-(2S)-hydroxy-5-phenyl-pentyl} carbamic acid tert-butyl ester 
• 126410-32-0 {(1S,2S,4R)-1-Benzyl-2-(tert-butyl-dimethyl-silanyloxy)-4-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-5-phenyl-pentyl}-carbamic acid tert-butyl ester 
• 98818-51-0 N-(1,1-dimethylethoxycarbonyl)-5(S)-amino-4(S)-(t-butyldimethylsilyloxy)-6-phenyl-2(R)-(phenylmethyl)hexanoic acid 
• 98818-45-2 5(S)-(Boc-amino)-4(S)-hydroxy-6-phenyl-2(R)-phenylmethylhexanoic acid 
• 98818-41-8 (3R,5S)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one 
• 38678-60-3 leucylphenylalanylamide 

Downstream Products

• 126409-24-3 {(1S)-benzyl-(4R)-[1-((1S)-carbamoyl-2-phenyl-ethylcarbamoyl)-(1S)-3-methyl-butyl-carbamoyl]-(2S)-hydroxy-5-phenyl-pentyl} carbamic acid tert-butyl ester 
• 292632-98-5 (5S)-(tert-butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl-L-leucy-L-phenylalaninamide 

Relevant articles and documents

Allyltrichlorostannane additions to α-amino aldehydes: Application to the total synthesis of the aspartyl protease inhibitors L-682,679, L-684,414, L-685,434, and L-685,458

The hydroxyethylene dipeptide isosteres L-682,679, L-684,414, L-685,434, and L-685,458 were synthesized in a few steps by a sequence involving an allyltrichlorostannane coupling with an α-amino aldehyde, followed by hydroboration of the corresponding 1,2-