292864-76-7

Upstream product

• 292864-74-5 3-deoxy-1,2-O-isopropylidene-3-methylidene-5-O-trityl-α-D-ribofuranose 
• 20590-53-8 1,2-O-isopropylidene-5-O-trityl-α-D-xylofuranose 
• 20590-54-9 1,2-O-isopropylidene-5-O-(triphenylmethyl)-α-D-erythro-pentofuranos-3-ulose 
• 292864-75-6 methyl 3-deoxy-3-methylene-D-erythro-pentofuranoside 

Downstream Products

• 292864-77-8 (3R,5S)-5-{{[(tert-butyl)diphenylsilyl]oxy}methyl}tetrahdyro-4-methylidenefuran-3-ol 
• 292864-85-8 3-benzoyl-{(3S,5S)-5-{{[(tert-butyl)diphenylsilyl]oxy}methyl}tetrahydo-4-methylidenefuran-3-yl}-5-methylpyrimidine-2,4(1H,3H)-dione 
• 292864-88-1 2-{(3S,5S)-5-{{[(tert-butyl)diphenylsilyl]oxy}methyl}tetrahydro-4-methylidenefuran-3-yl}-1H-isoindol-1,3(2H)-dione 
• 292864-79-0 3-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-methylene-tetrahydro-furan-3-yl]-3H-purin-6-ylamine 
• 292864-81-4 4-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-methylene-tetrahydro-furan-3-yl]-4H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamine 
• 292864-78-9 9-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-methylene-tetrahydro-furan-3-yl]-9H-purin-6-ylamine 
• 292864-80-3 3-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-methylene-tetrahydro-furan-3-yl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamine 
• 292864-87-0 Methanesulfonic acid (3R,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-4-methylene-tetrahydro-furan-3-yl ester 
• 292864-89-2 (3S,5S)-5-{{[(tert-butyl)diphenylsilyl]oxy}methyl}tetrahydro-4-methylidenefuran-3-amine 

Relevant academic research and scientific papers

Isonucleosides with exocyclic methylene groups

Synthesis of isonucleosides 13, 14, 16, and 17, bearing an exocyclic methylidene group at the sugar moiety, starting from a 3-keto sugar is described. The keto compound was converted to the methylene-sugar 10b (Scheme 1), which was coupled with nucleobase