29291-15-4

Basic information

• Product Name: 2,3-Diphenylthiazolidin-4-one
• Synonyms: 2,3-Diphenyl-4-thiazolidinone;2,3-Diphenylthiazolidin-4-one
• CAS NO: 29291-15-4
• Molecular Formula: C₁₅H₁₃NOS
• Molecular Weight: 255.33
• Mol File: 29291-15-4.mol
• Article Data: 45

Chemical Properties

• Boiling Point: 504.9 °C at 760 mmHg
• Flash Point: 259.2 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 2.55E-10mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 2,3-Diphenylthiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Diphenylthiazolidin-4-one(29291-15-4)
• EPA Substance Registry System: 2,3-Diphenylthiazolidin-4-one(29291-15-4)

Safety Data

• Hazardous Substances Data: 29291-15-4(Hazardous Substances Data)

Usage

Common Abbreviation

DPTH

Chemical Structure

Thiazolidine ring structure

Usage

Building block in synthesis of pharmaceutical drugs and biologically active compounds

Biological and Pharmacological Activities

Anti-inflammatory
Antimicrobial
Antifungal
Antitumor

Potential as an Anti-diabetic Agent

Regulates glucose levels
Improves insulin sensitivity

Additional Properties

Neuroprotective
Antioxidant

Promising for Research and Development

Versatile and valuable properties suggest potential for further exploration and application in various fields.

InChI:InChI=1/C15H13NOS/c17-14-11-18-15(12-7-3-1-4-8-12)16(14)13-9-5-2-6-10-13/h1-10,15H,11H2

Upstream product

• 68-11-1 mercaptoacetic acid 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 100-52-7 benzaldehyde 
• 623-51-8 ethyl 2-sulfanylacetate 
• 62-53-3 aniline 
• 100-51-6 benzyl alcohol 
• 126105-53-1 (Phenyl-phenylamino-methylsulfanyl)-acetic acid 
• 538-51-2 benzylidene phenylamine 
• 30298-36-3 2-mercaptothioacetic acid 
• 622-37-7 Phenyl azide 

Downstream Products

• 42056-23-5 5-(2-methoxybenzylidene)-2,3-diphenylthiazolidine-4-one 
• 1627745-63-4 2′′,3′′-diphenyl-4′-(4-tertbutylphenyl)-1′-methyldispiro[indole-3,2′-pyrrolidine-3′,5′′-[1,3]thiazolane]-2(1H),4′′-dione 
• 1627745-62-3 4′-(4-isopropylphenyl)-2′′,3′′-diphenyl-1′-methyldispiro[indole-3,2′-pyrrolidine-3′,5′′-[1,3]thiazolane]-2(1H),4′′-dione 
• 1627745-61-2 4′-(4-methylphenyl)-2′′,3′′-diphenyl-1′-methyldispiro[indole-3,2′-pyrrolidine-3′,5′′-[1,3]thiazolane]-2(1H),4′′-dione 
• 1627745-60-1 2'',3'', 4'-triphenyl-1'-methyldispiro[indole-3,2′-pyrrolidine-3′,5′′-[1,3]thiazolane]-2(1H),4′′-dione 

Relevant articles and documents

Regioselective synthesis of new 2,5,6-trisubstituted 5,6-dihydro-2H-pyrazolo[3,4-d]thiazoles from 5-dimethylaminoethylene-thaozolidin-4-thiones

Thiazolidin-4-ones assembled through one-pot three-component (carbonyl compound, amine and ethyl mercaptoacetate) reactions in the presence of dicyclohexyl carbodiimide, on simultaneous treatment with dimethyl formamide dimethylacetal and Lawesson's reage

Condensation–cyclization reaction for one-pot synthesis of 1,3-thiazolidin-4-one derivatives by poly(p-phenylenediamine) grafted on LDHs as a catalyst with green tool

The three-component reaction between amine, carbonyl compound and thioglycolic acid is now considered as a major strategy for synthesis of 1,3-thiazolidin-4-ones, which consists of the following steps: (i) condensation of aldehyde and amine which results

Visible-light-driven photocatalytic activity of ZnO/g-C3N4 heterojunction for the green synthesis of biologically interest small molecules of thiazolidinones

Designing a photocatalytic system with complementary properties including high surface area, high loading, extraordinary electronic properties, and easy separation for increases photocatalytic performance has remained a challenge in photocatalytic applications. Herein, an environmentally benign approach was developed to fabricate graphitic carbon nitride (g-C3N4) decorated with nanorods zinc oxide (ZnO). The photocatalytic activity of ZnO decorated on the g-C3N4 surface was developed in the synthesis of 1,3-thiazolidin-4-ones and bis-thiazolidinones under very mild and sustainable reaction conditions. The reaction can be carried out by utilizing visible light without the requirement of any additive and other external sources of energy. It was found that the proposed photocatalyst is a more facile, recyclable, large-scale application and provides some new insights into the stabilization of semiconductors for a variety of applications.