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2,3-Diphenylthiazolidin-4-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

29291-15-4

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29291-15-4 Usage

Common Abbreviation

DPTH

Chemical Structure

Thiazolidine ring structure

Usage

Building block in synthesis of pharmaceutical drugs and biologically active compounds

Biological and Pharmacological Activities

Anti-inflammatory
Antimicrobial
Antifungal
Antitumor

Potential as an Anti-diabetic Agent

Regulates glucose levels
Improves insulin sensitivity

Additional Properties

Neuroprotective
Antioxidant

Promising for Research and Development

Versatile and valuable properties suggest potential for further exploration and application in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 29291-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,2,9 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 29291-15:
(7*2)+(6*9)+(5*2)+(4*9)+(3*1)+(2*1)+(1*5)=124
124 % 10 = 4
So 29291-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NOS/c17-14-11-18-15(12-7-3-1-4-8-12)16(14)13-9-5-2-6-10-13/h1-10,15H,11H2

29291-15-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-diphenyl-1,3-thiazolidin-4-one

1.2 Other means of identification

Product number -
Other names 2,3-diphenylthiazolidin-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:29291-15-4 SDS

29291-15-4Relevant academic research and scientific papers

Regioselective synthesis of new 2,5,6-trisubstituted 5,6-dihydro-2H-pyrazolo[3,4-d]thiazoles from 5-dimethylaminoethylene-thaozolidin-4-thiones

Gautam, Poonam,Gautam, Deepika,Chaudhary

, p. 628 - 640 (2014)

Thiazolidin-4-ones assembled through one-pot three-component (carbonyl compound, amine and ethyl mercaptoacetate) reactions in the presence of dicyclohexyl carbodiimide, on simultaneous treatment with dimethyl formamide dimethylacetal and Lawesson's reage

Preparation of thiazolidin-4-one derivatives using ZnO–NiO–NiFe2O4 nano-composite system

Lashkari, Mojtaba,Ghashang, Majid

, p. 589 - 597 (2020/10/15)

The hydrothermal synthesis of ZnO–NiO–NiFe2O4 nano-composite is reported. The sample was utilized to characterize via XRD, FE-SEM, EDS, FT-IR, UV–Vis, and BET techniques. The sample consisted of three different phases as ZnO (hexagonal), NiO (cubic), and NiFe2O4 (cubic) with the average particle size as 34?nm and specific surface area, average pore diameter, and pore volume as 64.35?m2?g?1, 13.02?nm, and 0.201?cm3?g?1, respectively. Catalytic behavior of the nano-composite was investigated on the synthesis of thiazolidin-4-one derivatives under thermal and ultrasonic irradiation condition. Our results show that the catalytic activity of ZnO–NiO–NiFe2O4 nano-composite is much higher than ZnO, NiO, and NiFe2O4 metal oxides. All products were prepared in high yields with short reaction times. In addition, the catalyst was recovered for at least five times.

Condensation–cyclization reaction for one-pot synthesis of 1,3-thiazolidin-4-one derivatives by poly(p-phenylenediamine) grafted on LDHs as a catalyst with green tool

Mirzaei-Mosbat, Maryam,Ghorbani-Vaghei, Ramin

, p. 83 - 95 (2020/09/09)

The three-component reaction between amine, carbonyl compound and thioglycolic acid is now considered as a major strategy for synthesis of 1,3-thiazolidin-4-ones, which consists of the following steps: (i) condensation of aldehyde and amine which results

5-Benzylidene-2,3-diarylthiazolidine-4-ones: Design, synthesis, spectroscopic characterization, in vitro biological and computational evaluation

Saeedian Moghadam, Ebrahim,Sameem, Bilqees,Abdel-Jalil, Raid,Faramarzi, Mohammad Ali,Amini, Mohsen

supporting information, p. 2668 - 2683 (2021/07/19)

The synthesis and antidiabetic activity of 5-Benzylidene-2,3-diarylthiazolidine-4-one derivatives (6a–w) are presented in the current work. Screening of derivatives 6a–w for their α-glucosidase inhibitory activity, showed higher inhibitory activity of twe

Visible-light-driven photocatalytic activity of ZnO/g-C3N4 heterojunction for the green synthesis of biologically interest small molecules of thiazolidinones

Alamgholiloo, Hassan,Farajzadeh, Mustafa,Gholipour, Behnam,Khaksar, Samad,Mohammadi, Robabeh,Rostamnia, Sadegh,Shokouhimehr, Mohammadreza

, (2020/08/05)

Designing a photocatalytic system with complementary properties including high surface area, high loading, extraordinary electronic properties, and easy separation for increases photocatalytic performance has remained a challenge in photocatalytic applications. Herein, an environmentally benign approach was developed to fabricate graphitic carbon nitride (g-C3N4) decorated with nanorods zinc oxide (ZnO). The photocatalytic activity of ZnO decorated on the g-C3N4 surface was developed in the synthesis of 1,3-thiazolidin-4-ones and bis-thiazolidinones under very mild and sustainable reaction conditions. The reaction can be carried out by utilizing visible light without the requirement of any additive and other external sources of energy. It was found that the proposed photocatalyst is a more facile, recyclable, large-scale application and provides some new insights into the stabilization of semiconductors for a variety of applications.

Visible-light-promoted C[sbnd]N and C[sbnd]S bonds formation: A catalyst and solvent-free photochemical approach for the synthesis of 1,3-thiazolidin-4-ones

Ali, Shabir,Ansari, Khursheed,Ansari, Mohd Danish,Nazeef, Mohd,Shivhare, Km Neha,Siddiqui, I. R.,Tiwari, Saurabh K.,Yadav, Vikas

, (2020/01/02)

A visible-light-induced, one-pot mild and efficient, multicomponent-tandem synthesis of diversified 1,3-thiazolidin-4-ones under catalyst and solvent-free conditions is reported. Here, visible-light, an ideal source of energy, has been used as photochemic

Silica chloride (SiO2-Cl) catalyzed one pot synthesis of 2,3-disubstituted-thiazolidin-4-one

Gokhale, Kunal M.,Telvekar, Vikas N.

supporting information, p. 1396 - 1403 (2020/03/31)

In this paper, we report one-pot, three-component cyclo condensation of an aldehyde, an amine and thioglycolic acid to form 2,3-disubstituted-thiazolidin-4-one by using supported protic acid (Silica Chloride: SiO2-Cl) catalyst. The catalyst SiO2-Cl is compatible with a variety of aldehydes (aryl/heteroaryl) and the aromatic amines affording 2,3-disubstituted-thiazolidin-4-one analogs in 72–89% yields. Moreover, the supported catalyst was recycled several times without significant loss of catalytical activity.

Tromethamine organocatalyzed efficient tandem-multicomponent synthesis of new thiazolyl-4-thiazolidinones in aqueous medium

Bhosle, Manisha R.,Kharote, Sayali A.,Bondle, Giribala M.,Mali, Jyotirling R.

supporting information, p. 1286 - 1300 (2019/04/30)

The catalytic potential of tris(hydroxymethyl)aminomethane (Tromethamine) has been assessed for the one pot three component tandem reaction involving a thiazolylmethoxy phenyl/aromatic carboxaldehyde, substituted amines and thioglycolic acid to form new t

TS-1 zeolite as a Lewis acid catalyst for solvent-free one-pot synthesis of 1,3-thiazolidin-4-ones

Gadekar, Sachin P.,Lande, Machhindra K.

, p. 237 - 247 (2018/10/02)

Abstract: Titanium silicate (TS-1) zeolite heterogeneous catalyst is synthesized by the hydrothermally discontinuous method and is characterized by using XRD, SEM, TEM, and NH3–TPD techniques. The catalytic activity of the TS-1 type zeolite was tested for one-pot solvent-free synthesis of 1,3-thiazolidine-4-ones. The present technique illustrates many benefits, including eco-friendly reaction conditions, environmentally helpful, short response time, simplicity, straightforward separatation, catalyst reusability and high yields of the products. Furthermore, the catalyst was utilized for four recycle reactions and it has been found that the catalyst shows consistent chemical process activity. Graphical abstract: [Figure not available: see fulltext.].

Graphene oxide catalyzed C-N/C-S/[3+2] cyclization cascade for green synthesis of thiazolidinone in water

Mahata, Suhasini,Sahu, Anjumala,Shukla, Prashant,Rai, Ankita,Singh, Manorama,Rai, Vijai K.

, p. 665 - 672 (2018/07/14)

In this paper, first graphene oxide catalyzed one-pot three-component green synthesis of 1,3- thiazolidin-4-one using amine, aldehyde and mercapto acetic acid in water has been reported. The reaction is affected via sequential C-N and C-S bond formation a

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