29331-43-9 Usage
General Description
(1-chloro-3-cyano-propan-2-yl) acetate is a chemical compound with the formula C6H8ClNO2. It is a colorless liquid with a sharp, pungent odor and is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a solvent and in the production of plasticizers and polymers. (1-chloro-3-cyano-propan-2-yl) acetate is known to be irritant to the skin, eyes, and respiratory system and should be handled with care. It is important to follow safety precautions and use proper protective equipment when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 29331-43-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,3,3 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 29331-43:
(7*2)+(6*9)+(5*3)+(4*3)+(3*1)+(2*4)+(1*3)=109
109 % 10 = 9
So 29331-43-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H8ClNO2/c1-5(9)10-6(4-7)2-3-8/h6H,2,4H2,1H3
29331-43-9Relevant articles and documents
Preparation of (R)- and (S)-4-chloro-3-acetoxybutyronitrile using microbial resolution
Idogaki, Hideaki,Kasai, Naoya,Takeuchi, Motoko,Hatada, Miki,Suzuki, Toshio
, p. 369 - 373 (2007/10/03)
A new preparation of optically active 4-chloro-3-acetoxybutyronitrile (AcBN) was developed using the resting cells of bacteria. The resolution was based on enantioselective hydrolysis of the ester function of the substrate. (R)-AcBN was prepared using Pseudomonas sp. DS-K-717, and the resulting (R)-AcBN was obtained with high enantiomeric excess of >98% with a yield of 36% during the microbial resolution step. (S)-AcBN was prepared in the same manner using the resting cells of Pseudomonas sp. DS-K-19 and showed a high enantiomeric excess of >98% with a yield of 32%. The enzyme activity was enhanced and induced by the addition of AcBN, particularly the (R)-ester hydrolysis, which was enhanced 20-fold.
