293737-68-5

Basic information

• Product Name: 3-BENZOOXAZOL-2-YL-4-CHLORO-PHENYLAMINE
• Synonyms: ASISCHEM T30927;ART-CHEM-BB B025229;3-BENZOOXAZOL-2-YL-4-CHLORO-PHENYLAMINE;AKOS BB-8191
• CAS NO: 293737-68-5
• Molecular Formula: C₁₃H₉ClN₂O
• Molecular Weight: 244.68
• Mol File: 293737-68-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BENZOOXAZOL-2-YL-4-CHLORO-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZOOXAZOL-2-YL-4-CHLORO-PHENYLAMINE(293737-68-5)
• EPA Substance Registry System: 3-BENZOOXAZOL-2-YL-4-CHLORO-PHENYLAMINE(293737-68-5)

Safety Data

• Hazardous Substances Data: 293737-68-5(Hazardous Substances Data)

Upstream product

• 25784-91-2 2-chloro-5-nitrobenzoylchloride 
• 95-55-6 2-amino-phenol 
• 89-54-3 2-chloro-5-aminobenzoic acid 

Downstream Products

• 431937-77-8 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)furan-2-carboxamide 
• 313483-84-0 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)-2-fluorobenzamide 
• 885304-75-6 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)-2-methylbenzamide 
• 420106-20-3 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)-3-fluorobenzamide 
• 432002-47-6 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)-3-methylbenzamide 
• 886784-51-6 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)cyclohexanecarboxamide 
• 442524-44-9 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)benzamide 
• 431983-11-8 N-(3-(benzo[d]oxazol-2-yl)-4-chlorophenyl)-3,4,5-triethoxybenzamide 

Relevant articles and documents

3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis

A whole organism high-throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei led to the recent discovery of several novel compound classes with low micromolar activity against this organism and without appreciable cytotoxici

MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES

The present invention relates to phthalimide carboxylic acid derivatives of formula (I), methods for their preparation, pharmaceutical compositions containing them and their use in medicine, specifically in the treatment of cancer. (I), wherein X is O or S; R1 is a phthalimide carboxylic acid group of formula (II). R is hydrogen, C1-C6 alkyl, aryl or C1-C3 alkylaryl and R2, R3 and R4 represent various substituents.

Benzoxazole LPAAT-B inhibitors and uses thereof

The invention relates to benzoxazoles and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said benzoxazoles. The invention also relates to methods for screening for LPAAT-β activity.