2941-73-3Relevant academic research and scientific papers
A charge transfer type pH responsive fluorescent probe and its intracellular application
Liu, Zhipeng,Zhang, Changli,He, Weijiang,Qian, Fang,Yang, Xiaoliang,Gao, Xiang,Guo, Zijian
scheme or table, p. 656 - 660 (2010/06/18)
A new charge transfer pH fluorescent probe BTP has been prepared by the ethylene bridging of benzothiazole and pyridine. The probe exhibits a specific fluorescent response to pH with a large Stokes shift, and the pH-induced emission enhancement factor (EEF) is about 22-fold when the pH is increased from 3.2 to 5.2. The presence of metal cations such as Na+, K +, Ca2+, Mg2+ and other transition metal cations does not interfere with its fluorescent pH response. In addition, the intracellular pH fluorescent imaging ability of the probe has been confirmed on macrophage cells using a confocal microscope. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.
Preparation of novel push-pull benzothiazole derivatives with reverse polarity: Compounds with potential non-linear optic application
Hrobarik, Peter,Sigmundova, Ivica,Zahradnik, Pavol
, p. 600 - 604 (2007/10/03)
The hitherto unknown 6-dimethylaminobenzothiazole-2-carbaldehyde was prepared as a starting compound for the synthesis of novel push-pull benzothiazole derivatives with reverse polarity. These compounds are substituted at the 2-position by strong electron-acceptor groups and at the 6-position by NMe2 as strong electron-donor. The new method for synthesis of 6-dimethylaminobenzothiazole involved the successful use of sonochemical reductive methylation. Expected non-linear optical properties of target molecules were studied by EFISH method.
