294176-84-4

Upstream product

• 359-41-1 1,1,1-trifluoro-2,3-epoxypropane 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 

Downstream Products

• 294176-87-7 [(1R,2S)-1-(3,4-Dimethoxy-phenyl)-2-trifluoromethyl-cyclopropyl]-carbamic acid tert-butyl ester 
• 294176-86-6 2-trifluoromethyl-1-(3,4-dimethoxyphenyl)cyclopropylcarboxamide 
• 294176-85-5 2-trifluoromethyl-1-(3,4-dimethoxyphenyl)cyclopropyl cyanide 

Relevant academic research and scientific papers

Syntheses of optically active trifluoronorcoronamic acids.

Syntheses of optically active trifluoronorcoronamic acid 6 and its diastereomer 9 are described. Highly stereospecific and diastereoselective S(N)2 cyclization of gamma-cyanohydrins 3a and 3b gave cyclopropyl nitriles 4a and 4b. Hydrolysis of the cyano gr