29430-39-5

Basic information

• Product Name: 3-METHYLPHENYL CHLOROFORMATE
• Synonyms: 3-METHYLPHENYL CHLOROFORMATE;m-tolyl chloroformate;Chloroformic acid 3-methylphenyl ester
• CAS NO: 29430-39-5
• Molecular Formula: C₈H₇ClO₂
• Molecular Weight: 170.59
• EINECS: 249-625-2
• Mol File: 29430-39-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 214.4°Cat760mmHg
• Flash Point: 93°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 0.156mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: 3-METHYLPHENYL CHLOROFORMATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYLPHENYL CHLOROFORMATE(29430-39-5)
• EPA Substance Registry System: 3-METHYLPHENYL CHLOROFORMATE(29430-39-5)

Safety Data

• Hazardous Substances Data: 29430-39-5(Hazardous Substances Data)

Usage

General Description

3-Methylphenyl chloroformate, also known as m-tolyl chloroformate, is an organic compound that consists of a phenyl group, a methyl group, and a chloroformate group. It is a colorless or pale yellow liquid with a pungent odor and is commonly used as a reagent in organic synthesis. It is utilized in the production of pharmaceuticals, agrochemicals, and advanced materials. The compound is known to be corrosive and can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. It is important to handle and store 3-methylphenyl chloroformate with caution and in compliance with safety protocols.

InChI:InChI=1/C8H7ClO2/c1-6-3-2-4-7(5-6)11-8(9)10/h2-5H,1H3

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 108-39-4 3-methyl-phenol 
• 75-44-5 phosgene 

Downstream Products

• 78258-80-7 4-methyl-3H-benzooxazol-2-one 
• 22876-16-0 6-methylbenzoxazolin-2-one 
• 724-48-1 Chlorameisensaeure-<4-nitro-3-trichlormethyl-phenylester> 
• 1085-46-7 Isopropyl-<3-trichlormethyl-phenyl>-carbonat 
• 22134-44-7 α-Chloro-m-tolyl-N-(3.4-dichlorophenyl)carbamat 
• 22134-43-6 α-Chloro-m-tolyl-N-(p-chlorophenyl)carbamat 
• 22134-42-5 α-Chloro-m-tolyl-N-(m-chlorophenyl)carbamat 
• 22132-67-8 α-Chloro-m-tolyl-N-methylcarbamat 
• 22134-41-4 α-Chloro-m-tolyl-N-phenylcarbamat 
• 108718-04-3 (cis-4-hydroxy-cyclohexyl)-carbamic acid m-tolyl ester 
• 108719-60-4 (+/-)-(cis-3-hydroxy-cyclohexyl)-carbamic acid m-tolyl ester 
• 164297-04-5 C₁₈H₁₈N₂O₄S 
• 83498-81-1 N-Isopropyl-carbaminsaeure-m-tolylester 
• 1847-82-1 Kohlensaeure-butyl-m-tolyl-ester 

Relevant articles and documents

Versatile Cp*Co(III)(LX) Catalyst System for Selective Intramolecular C-H Amidation Reactions

Herein, we report the development of a tailored cobalt catalyst system of Cp*Co(III)(LX) toward intramolecular C-H nitrene insertion of azidoformates to afford cyclic carbamates. The cobalt complexes were easy to prepare and bench-stable, thus offering a convenient reaction protocol. The catalytic reactivity was significantly improved by the electronic tuning of the bidentate LX ligands, and the observed regioselectivity was rationalized by the conformational analysis and DFT calculations of the transition states. The superior performance of the newly developed cobalt catalyst system could be broadly applied to both C(sp2)-H and C(sp3)-H carbamation reactions under mild conditions.

Preparation of chloroformates using bis(trichloromethyl)carbonate

The synthesis of eight chloroformates using bis(trichloromethyl) carbonate(BTC) is reported. It has been found that the yields by this BTC method are improved over the earlier phosgene method, and sodium hydroxide is better than pyridine as catalyst for the preparation of phenyl chloroformate.