29442-43-1

Basic information

• Product Name: Silacyclohexane, 1-chloro-1-phenyl-
• CAS NO: 29442-43-1
• Molecular Formula: C11H15ClSi
• Molecular Weight: 210.779
• Mol File: 29442-43-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Silacyclohexane, 1-chloro-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silacyclohexane, 1-chloro-1-phenyl-(29442-43-1)
• EPA Substance Registry System: Silacyclohexane, 1-chloro-1-phenyl-(29442-43-1)

Safety Data

• Hazardous Substances Data: 29442-43-1(Hazardous Substances Data)

Upstream product

• 98-13-5 Phenyltrichlorosilane 
• 23708-48-7 pentamethylenebis(magnesium bromide) 
• 85125-33-3 1-phenyl-1-silacyclohexane 
• 108-90-7 chlorobenzene 
• 111-24-0 1,5-dibromo-pentane 
• 2406-34-0 1,1-dichloro-1-silacyclohexane 

Downstream Products

• 18753-43-0 1,1'-diphenyl-1,1'bi(silacyclohexyl) 
• 85125-33-3 1-phenyl-1-silacyclohexane 
• 18753-38-3 (1,1'-phenyl-1,1'-silacyclohex-1-yl)disiloxane 

Relevant articles and documents

1-t-Butyl-1-phenyl-1-silacyclohexane: Synthesis, conformational analysis in gas and solution by GED, FT-IR and theoretical calculations

1-t-Butyl-1-phenyl-1-silacyclohexane 1, the first disubstituted silacyclohexane with the most bulky substituent, t-Bu group, at silicon, was synthesized via the sequence of reactions PhSiCl3 → Ph(Cl)Si(CH2)5 → Ph(t-Bu)Si(C

Entecavir intermediate and its preparation method

The invention discloses an entecavir intermediate and a preparation method thereof. A provided preparation method for an entecavir intermediate compound 8 comprises the following steps: performing hydroxyl protection group removal reaction on a compound 9 in a solvent under an acidic condition, so as to obtain the compound 8. A provided preparation method for an entecavir intermediate compound 9 comprises the following steps: performing hydroxyl protection group adding reaction on a compound 10 in an aprotic organic solvent under an alkali condition, so as to obtain the compound 9. The preparation methods are cheap and easily available in raw materials, mild in reaction conditions, relatively high in product yield, good in atom economy, friendly to environment, and suitable for industrialized production.

Entecavir intermediate and its preparation method

The invention discloses an entecavir intermediate and a preparation method thereof. A provided preparation method for an entecavir intermediate compound 10 comprises the following steps: performing reducing reaction on an ester compound 11 in an organic solvent under the effect of a reducing agent, so as to obtain the compound 10. A provided preparation method for an entecavir intermediate compound 11 comprises the following steps: reacting a compound 12 with a hydroxyl protection reagent in an organic solvent in the presence of an acid to add a hydroxyl protection group, so as to obtain the compound 11. The preparation methods are cheap and easily available in raw materials, mild in reaction conditions, relatively high in product yield, good in atom economy, friendly to environment, and suitable for industrialized production.