29449-73-8Relevant academic research and scientific papers
Substituted indole compound and method and use thereof
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Paragraph 0245; 0247-0248, (2019/01/22)
The invention relates to a new indole compound, a drug composition which contains the new indole compound and a receptor for selectivity inhibiting 5-hydroxytryptamine reuptake and/or exciting 5-HT1A. The invention also relates to a method for preparing t
Deuterodechlorination of Aryl/Heteroaryl Chlorides Catalyzed by a Palladium/Unsymmetrical NHC System
Kuriyama, Masami,Hamaguchi, Norihisa,Yano, Gemba,Tsukuda, Kotaro,Sato, Kanako,Onomura, Osamu
, p. 8934 - 8946 (2016/10/14)
The catalytic deuterodechlorination of aryl/heteroaryl chlorides was developed with a palladium/unsymmetrical NHC system, and the precisely controlled introduction of deuterium into a variety of aryl/heteroaryl compounds was achieved with a high level of efficiency, selectivity, and deuteration degree. This method was also successfully applied to the transformation of bioactive agents even in a gram-scale synthesis. The crystal structure analysis of Pd-NHC complexes led to the observation of Pd-arene interaction.
PHENYL METHANESULFONAMIDE DERIVATIVES USEFUL AS MGAT - 2 INHIBITORS
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Page/Page column 14, (2013/08/15)
The present invention provides compounds of Formula I or a pharmaceutical salt thereof, where the variables for R1, R2, and R3 are as described herein; methods of treating a condition such as hypertriglyceridemia; and processes for preparing the compounds.
Herbicidal 2,6-substituted pyridines
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, (2008/06/13)
A herbicidal composition which comprises at least one carrier and, as active ingredient, a compound of the general formula STR1 in which each of n and m independently is 0 or 1; each of Ar1 and Ar2 independently is an aryl group, at least one of Ar1 and Ar2 being substituted by one or more of the same or different substituents selected from halogen atoms, alkyl groups, alkoxy groups, haloalkyl groups and haloalkoxy groups; and R1 is hydrogen, or an alkyl, alkylthio or haloalkyl group having from 1 to 4 carbon atoms, and R2 is hydrogen or a halogen atom provided that at least one of R1 and R2 represents a hydrogen atom. Certain compounds of formula I are novel.
2-(3-Amino-2-hydroxy-propoxy)-mono-and diazines
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, (2008/06/13)
Heterocyclic compounds of the formula STR1 wherein Het denotes optionally substituted pyridazinyl, pyrimidinyl, pyrazinyl or substituted pyridyl, R1 is hydrogen or methyl and R2 is lower alklyl, optionally substituted phenyl-lower alkyl, carboxy-lower alkyl or functionally modified carboxy-lower alkyl, their condensation products with aldehydes, ketones or carbonic acid and their N-oxides, which are valuable (cardioselective) β-receptor blocking agents, and/or (cardioselective) β-receptor-stimulants.
