29461-69-6Relevant academic research and scientific papers
Iron-catalyzed regiodivergent alkyne hydrosilylation
Hu, Meng-Yang,He, Peng,Qiao, Tian-Zhang,Sun, Wei,Li, Wen-Tao,Lian, Jie,Li, Jin-Hong,Zhu, Shou-Fei
, p. 16894 - 16902 (2020/10/09)
Although tremendous effort has been devoted to the development of methods for iron catalysis, few of the catalysts reported to date exhibit clear superiority to other metal catalysts, and the mechanisms of most iron catalysis remain unclear. Herein, we report that iron complexes bearing 2,9-diaryl-1,10-phenanthroline ligands exhibit not only unprecedented catalytic activity but also unusual ligand-controlled divergent regioselectivity in hydrosilylation reactions of various alkynes. The hydrosilylation protocol described herein provides a highly efficient method for preparing useful di- and trisubstituted olefins on a relatively large scale under mild conditions, and its use markedly improved the synthetic efficiency of a number of bioactive compounds. Mechanistic studies based on control experiments and density functional theory calculations were performed to understand the catalytic pathway and the observed regioselectivity.
Cyclic Vinyl(aryl)iodonium Salts: Synthesis and Reactivity
Kepski, Konrad,Rice, Craig R.,Moran, Wesley J.
supporting information, p. 6936 - 6939 (2019/09/30)
A convenient, highly regioselective synthesis of five-membered cyclic vinyl(aryl)iodonium salts directly from β-iodostyrenes is presented. An X-ray crystal structure confirms the identity of these heterocycles. These λ3-iodanes can be converted
Mild conversion of alkenyl boronic acids to alkenyl halides with halosuccinimides
Petasis, Nicos A.,Zavialov, Ilia A.
, p. 567 - 570 (2007/10/02)
Reaction of alkenyl boronic acids with halosuccinimides (NIS, NBS or NCS) gives the corresponding alkenyl halides with the same geometry. This method is suitable for the synthesis of geometrically pure (E) and (Z) alkenyl halides, as well as 1,1- and 1,2-
A direct and stereoselective route to (Z)-2-iodoalk-2-enes via β-oxido phosphonium ylides
Shen, Yanchang,Gao, Shu
, p. 1331 - 1332 (2007/10/02)
(Z)-2-Iodoalk-2-enes have been synthesized with high stereoselectivity by direct reaction of β-oxido phosphonium ylides with 1,2-diiodoethane.
