29536-41-2

Usage

Uses

Used in Pharmaceutical Applications:
3’,4’,5’-Trihydroxy-6,7-dimethoxyflavone is used as a natural compound for its potential health benefits in treating diseases such as cancer, diabetes, and heart disease. Its ability to scavenge free radicals and reduce oxidative stress contributes to its potential as a therapeutic agent.
Used in Nutraceutical Industry:
In the nutraceutical industry, 3’,4’,5’-Trihydroxy-6,7-dimethoxyflavone is used as a dietary supplement for its antioxidant properties, aiming to support overall health and well-being by combating the negative effects of oxidative stress.
Used in Cosmetic Industry:
3’,4’,5’-Trihydroxy-6,7-dimethoxyflavone is used as an ingredient in cosmetic products for its anti-inflammatory and skin-protective properties, potentially aiding in the reduction of skin inflammation and promoting skin health.
Further research is necessary to fully understand the potential benefits and mechanisms of action of 3’,4’,5’-Trihydroxy-6,7-dimethoxyflavone, ensuring its safe and effective application in various industries.

InChI:InChI=1/C17H14O7/c1-22-11-7-10-12(14(20)17(11)23-2)13(19)15(21)16(24-10)8-3-5-9(18)6-4-8/h3-7,18,20-21H,1-2H3

Upstream product

• 124910-03-8 2-(4-Benzyloxy-phenyl)-3,5-dihydroxy-6,7-dimethoxy-chromen-4-one 
• 1312097-78-1 sesuvioside A 
• 124909-99-5 Toluene-4-sulfonic acid 2-(4-benzyloxy-phenyl)-3-hydroxy-6,7-dimethoxy-4-oxo-4H-chromen-5-yl ester 
• 14801-88-8 2-(4-Benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one 
• 14801-90-2 2-(4-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one 
• 14639-73-7 1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone 
• 1486-49-3 p-(benzyloxy)benzoic acid anhydride 
• 124909-92-8 Toluene-4-sulfonic acid 2-(4-benzyloxy-phenyl)-3,6,7-trimethoxy-4-oxo-4H-chromen-5-yl ester 

Downstream Products

• 4472-73-5 3,5,6,7,4'-pentamethoxyflavone 

Relevant academic research and scientific papers

Flavonol 3-O-robinobiosides and 3-O-(2″-O-α-rhamnopyranosyl)- robinobiosides from Sesuvium portulacastrum

Six new flavonol 3-O-robinobiosides and 3-O-(2″-O-α-l- rhamnopyranosyl)-robinobiosides, sesuviosides A-F, were isolated from the aerial portion of Sesuvium portulacastrum together with ecdysterone, adenosine, 2′-O-methyladenosine, and l-tryptophan. The structure elucidations were based on analyses of chemical and spectroscopic data including 1D and 2D-NMR. Sesuviosides A-F and their aglycones exhibited radical scavenging activity using DPPH and ORAC assays.

STUDIES OF THE SELECTIVE O-ALKYLATION AND DEALKYLATION OF FLAVONOIDS. XII. A NEW, CONVENIENT METHOD FOR SYNTHESIZING 3,5-DIHYDROXY-6,7-DIMETHOXYFLAVONES FROM 3,5,6,7-TETRAMETHOXYFLAVONES

The 5-methoxy group on 3,5,6,7-tetramethoxyflavones and the 3-methoxy group on 3,6,7-trimethoxy-5-tosyloxy-flavones were selectively cleaved with anhydrous aluminum bromide in acetonitrile under controlled conditions without the cleavage of benzyloxy groups on the B ring.By the application of these reactions, seven 3,5-dihydroxy-6,7-dimethoxyflavones were easily synthesized from the corresponding 3,5,6,7-tetramethoxyflavones which were synthesized from 3,6-dihydroxy-2,4ω-trimethoxycetophenone by means of the Allan-Robinson reaction followed by methylation.Keywords: Allan-Robinson reaction ; selective demethylation; 3,5,6,7-tetramethoxyflavone; 5-hydroxy-3,6,7-trimethoxyflavone; 6-hydroxy-3,5,7-trimethoxyflavone; 5-tosyloxyflavone; 5,6-dihydroxy-3,7-dimethoxyflavone; 3,5-dihydroxy-6,7-dimethoxyflavone, 3,5-diacetoxy-6,7-dimethoxyflavone