29536-44-5

Basic information

• Product Name: Eupatolitin
• Synonyms: Eupatolitin;2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one;3,3',4',5-Tetrahydroxy-6,7-dimethoxyflavone;Eupatoletin
• CAS NO: 29536-44-5
• Molecular Formula: C₁₇H₁₄O₈
• Molecular Weight: 346.28800
• Mol File: 29536-44-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 640oC at 760 mmHg
• Flash Point: 238.7oC
• Appearance: /
• Density: 1.591g/cm3
• Vapor Pressure: 2.94E-17mmHg at 25°C
• Refractive Index: 1.707
• PKA: 6.13±0.40(Predicted)
• CAS DataBase Reference: Eupatolitin(CAS DataBase Reference)
• NIST Chemistry Reference: Eupatolitin(29536-44-5)
• EPA Substance Registry System: Eupatolitin(29536-44-5)

Safety Data

• Hazardous Substances Data: 29536-44-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A tetrahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 5, 3' and 4' and methoxy groups at positions 6 and 7 respectively.

InChI:InChI=1/C17H14O8/c1-23-11-6-10-12(14(21)17(11)24-2)13(20)15(22)16(25-10)7-3-4-8(18)9(19)5-7/h3-6,18-19,21-22H,1-2H3

Upstream product

• 1312097-82-7 sesuvioside C 
• 124909-95-1 Toluene-4-sulfonic acid 2-(3,4-bis-benzyloxy-phenyl)-3,6,7-trimethoxy-4-oxo-4H-chromen-5-yl ester 
• 124909-80-4 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one 
• 124910-02-7 3',4'-bis(benzyloxy)-3-hydroxy-6,7-dimethoxy-5-(tosyloxy)flavone 
• 24160-94-9 2-(3,4-Bis-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one 
• 14639-73-7 1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone 
• 1592-48-9 3,4-bis-benzyloxy-benzoic acid-anhydride 
• 29725-50-6 6,7-dimethoxy-3,5,3',4'-tetrahydroxyflavone 3-O-rhamnoside 
• 124910-06-1 2-(3,4-Bis-benzyloxy-phenyl)-3,5-dihydroxy-6,7-dimethoxy-chromen-4-one 

Downstream Products

• 1251-84-9 3,5,6,7,3',4'-Hexamethoxyflavon 
• 29536-45-6 3,3',4',5-Tetraacetoxy-6,7-dimethoxyflavon 

Relevant articles and documents

Flavonol 3-O-robinobiosides and 3-O-(2″-O-α-rhamnopyranosyl)- robinobiosides from Sesuvium portulacastrum

Six new flavonol 3-O-robinobiosides and 3-O-(2″-O-α-l- rhamnopyranosyl)-robinobiosides, sesuviosides A-F, were isolated from the aerial portion of Sesuvium portulacastrum together with ecdysterone, adenosine, 2′-O-methyladenosine, and l-tryptophan. The structure elucidations were based on analyses of chemical and spectroscopic data including 1D and 2D-NMR. Sesuviosides A-F and their aglycones exhibited radical scavenging activity using DPPH and ORAC assays.

STUDIES OF THE SELECTIVE O-ALKYLATION AND DEALKYLATION OF FLAVONOIDS. XII. A NEW, CONVENIENT METHOD FOR SYNTHESIZING 3,5-DIHYDROXY-6,7-DIMETHOXYFLAVONES FROM 3,5,6,7-TETRAMETHOXYFLAVONES

The 5-methoxy group on 3,5,6,7-tetramethoxyflavones and the 3-methoxy group on 3,6,7-trimethoxy-5-tosyloxy-flavones were selectively cleaved with anhydrous aluminum bromide in acetonitrile under controlled conditions without the cleavage of benzyloxy groups on the B ring.By the application of these reactions, seven 3,5-dihydroxy-6,7-dimethoxyflavones were easily synthesized from the corresponding 3,5,6,7-tetramethoxyflavones which were synthesized from 3,6-dihydroxy-2,4ω-trimethoxycetophenone by means of the Allan-Robinson reaction followed by methylation.Keywords: Allan-Robinson reaction ; selective demethylation; 3,5,6,7-tetramethoxyflavone; 5-hydroxy-3,6,7-trimethoxyflavone; 6-hydroxy-3,5,7-trimethoxyflavone; 5-tosyloxyflavone; 5,6-dihydroxy-3,7-dimethoxyflavone; 3,5-dihydroxy-6,7-dimethoxyflavone, 3,5-diacetoxy-6,7-dimethoxyflavone