29550-53-6

Upstream product

• 18665-81-1 (E)-3-methyl-5-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)pent-2-en-1-ol 
• 17283-81-7 4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on 
• 4179-00-4 Methyl (E)-3-methyl-5-(2,6,6-trimethylcyclohexen-1-yl)-2-pentenoate 

Downstream Products

• 158322-09-9 N'-[(E)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-5-methyl-7-(2,6,6-trimethyl-cyclohex-1-enyl)-hept-4-en-(E)-ylidene]-N,N-dimethyl-hydrazine 
• 105426-92-4 4-[(3Z,7E)-4-Dimethoxymethyl-1-(1-ethoxy-ethoxy)-8-methyl-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dienyl]-5-hydroxy-5H-furan-2-one 
• 105426-91-3 {4-[(3Z,7E)-4-Dimethoxymethyl-1-(1-ethoxy-ethoxy)-8-methyl-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dienyl]-furan-2-yl}-trimethyl-silane 
• 80388-51-8 manoalide-2-methyl ether 
• 75088-80-1 5-Hydroxy-4-{6-hydroxy-5-[(E)-4-methyl-6-(2,6,6-trimethyl-cyclohex-1-enyl)-hex-3-enyl]-3,6-dihydro-2H-pyran-2-yl}-5H-furan-2-one 
• 105498-76-8 seco-manoalide 
• 105426-86-6 (2Z,6E)-3-Dimethoxymethyl-7-methyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,6-dienoic acid tert-butyl ester 
• 105426-86-6 (2E,6E)-3-Dimethoxymethyl-7-methyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,6-dienoic acid tert-butyl ester 
• 105426-94-6 (2Z,6E)-3-Dimethoxymethyl-7-methyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,6-dien-1-ol 
• 105426-85-5 (E)-1,1-Dimethoxy-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-oct-5-en-2-one 
• 112503-50-1 2-((3E,7Z)-9-Chloro-7-dimethoxymethyl-3-methyl-nona-3,7-dienyl)-1,3,3-trimethyl-cyclohexene 
• 158322-16-8 ethyl (2Z,6E)-3-<<(tert-butyl)dimethylsiloxy>methyl>-7-methyl-9-(2',6',6'-trimethylcyclohex-1'-enyl)nona-2,6-dienoate 
• 158322-17-9 (2Z,6E)-3-<<(tert-butyl)dimethylsiloxy>methyl>-7-methyl-9-(2',6',6'-trimethylcyclohex-1'-enyl)nona-2,6-dien-1-ol 
• 158322-10-2 (E)-1-<(tert-butyl)dimethylsiloxy>-6-methyl-8-(2',6',6'-trimethylcyclohex-1'-enyl)oct-5-en-2-one 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF MANOALIDE AND SECO-MANOALIDE

The first synthesis of manoalide and seco-manoalide from methyl 7,8-dihydro-β-ionylidene acetate was achieved in high yield by the new method utilizing regiospecific singlet oxigen oxidation of 3-alkenyl-5-trimethylsilylfuran to β-alkenyl-γ-hydroxybutenol

A concise synthesis of (E)- and (Z)-neomanoalides

The first synthesis of (Z)-neomanoalide (4) and an improved synthesis of its (E)-isomer 3 was accomplished in a concise, regiocontrolled manner by exploiting 2-[(tert-butyl)dimethylsiloxy]-4{[(tert-butyl)dimethylsiloxy]methyl} furan (6) as the key reagent