29584-68-7

Upstream product

• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 471-25-0 Propiolic acid 
• 4392-24-9 Cinnamyl bromide 
• 920-38-7 sodium propargylate 
• 102-92-1 Cinnamoyl chloride 
• 104-54-1 3-Phenylpropenol 

Downstream Products

• 1138619-06-3 (E,E)-3-phenylallyl 3-(1H-indol-3-yl)acrylate 
• 1138619-09-6 (E)-3-phenylallyl 3,3-bis-(1H-indol-3-yl)propanoate 
• 1138619-11-0 (E,E)-3-phenylallyl 3-(2,4,6-trimethoxyphenyl)acrylate 
• 1138619-15-4 (E)-3-phenylallyl 3,3-bis-(2,4,6-trimethoxyphenyl)propanoate 
• 40918-97-6 3-phenyl-2-propen-1-yl 3-phenylacrylate 
• 1379515-65-7 C₂₂H₁₇Cl₂NO₄ 
• 215119-35-0 C₂₂H₁₈ClNO₄ 
• 1379515-64-6 C₂₂H₁₈ClNO₄ 
• 1379515-66-8 C₂₃H₁₈F₃NO₄ 
• 1379515-85-1 C₂₅H₂₀Cl₂N₂O₄ 
• 215120-03-9 C₂₅H₂₁ClN₂O₄ 
• 1379515-84-0 C₂₅H₂₁ClN₂O₄ 
• 1379515-86-2 C₂₆H₂₁F₃N₂O₄ 
• 1379515-88-4 4-(3,5-dichloro-4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-cinnamyl ester 5-(2-cyanoethyl) ester 

Relevant academic research and scientific papers

INTRAMOLECULAR CYCLIZATION OF ALLYLIC PROPIOLATES MEDIATED BY THE ADDITION OF STANNYL RADICALS: A NEW SYNTHETIC ROUTE TO α-METHYLENE-γ-BUTYROLACTONES

Allylic propiolates react with tributyl- or triphenylstannane to yield α-(stannyl)methylene-γ-butyrolactones. α-Methylene-γ-butyrolactones are easily prepared by destannylation.

Dihydropyridine derivative

Dihydropyridine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an activity of selectively inhibiting the action of N-type calcium channel. They are used as remedies for various diseases relating to the N-type calcium channel such as encephalopathies caused by the ischemia in the acute phase after the onset of cerebral infarction, cerebral hemorrhage or the like, Alzheimer's disease, etc.

Stereoselective Synthesis of α-(Chloromethylene)-γ-butyrolactone Derivatives from Acyclic Allylic 2-Alkynoates

α-Methylene-γ-butyrolactones have been constructed by a bis(benzonitrile)palladium dichloride catalyzed cyclization reaction of the easily available acyclic 2'-alkenyl 2-alkynoates in the presence of CuCl2.A mechanism involving a stereoselective chloropalladation in the presence of CuCl2, followed by intramolecular insertion of a carbon-carbon double bond to the carbon-palladium bond, and subsequent CuCl2-mediated formation of a new carbon-chlorine bond is briefly discussed.

IMPROVED PREPARATION OF ALIPHATIC PROPYNOIC ESTERS

An improved procedure of esterification of propynoic acid, based on the N,N'-dicyclohexylcarbodiimide 4-dimethylaminopyridine condensation, is presented, which gives good results with primary, secondary, allylic and homoallylic alcohols.Reactions conditions are mild.Some limitations are given.