29618-28-8

Usage

Uses

Used in Pharmaceutical Industry:
Benzamide, N-[2-methyl-1-[(phenylamino)carbonyl]propyl]-, (S)is used as a pharmaceutical compound for its potential therapeutic effects. Its unique structure and chirality may contribute to its interaction with specific biological targets, making it a candidate for the development of new drugs.
Used in Research Applications:
In the field of research, Benzamide, N-[2-methyl-1-[(phenylamino)carbonyl]propyl]-, (S)serves as a valuable tool for studying the effects of chirality on chemical and biological properties. It can be used to investigate the stereoselectivity of enzymatic reactions, receptor binding, and other processes that are influenced by the spatial arrangement of molecules.
Used in Industrial Applications:
Due to its unique structure and properties, Benzamide, N-[2-methyl-1-[(phenylamino)carbonyl]propyl]-, (S)may also find use in various industrial applications. For example, it could be employed as an intermediate in the synthesis of other compounds, or utilized in the development of new materials with specific properties.

Upstream product

• 98-88-4 benzoyl chloride 
• 129473-55-8 (S)-2-amino-3-methyl-N-phenylbutanamide 
• 65-85-0 benzoic acid 
• 3057-79-2 N-benzoyl-valine anilide 
• 16876-74-7 (S)-benzyl (3-methyl-1-oxo-1-(phenylamino)butan-2-yl)carbamate 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 72-18-4 L-valine 
• 62-53-3 aniline 
• 2901-80-6 N-benzoyl-D,L-valine 

Relevant academic research and scientific papers

A study of the strength of a template molecule - A functional monomer interaction that affects the performance of molecularly imprinted polymers and its application to chiral amplification

A novel type of molecularly imprinted polymer (MIP), N-benzoyl-(S)-valine anilide-imprinted polymer (IP-2), was prepared using hydrogen-bonding interactions as a main force in the pre-polymerization step. The performance of the IP-2 was evaluated via batch procedure and compared with a (S)-valine anilideimprinted polymer (IP-1) that was prepared using an ionic interaction that is stronger than hydrogen bonding. Although both polymers showed a preferential adsorbability for (S)-amino acid derivatives, different performances were observed in terms of adsorbability and enantioselectivity. In addition, the IP-2 was able to recognize the enantiomer of a valine-derived chiral catalyst. This phenomenon was applied to a chiral amplification reaction, and a highly selective asymmetric Mannich-type amination was achieved using the combination of a racemic catalyst and a MIP.

Pd-catalyzed enantioselective synthesis of quaternary α-amino acid derivatives using a phenylalanine-derived P-chirogenic diaminophosphine oxide

A Pd-catalyzed enantioselective synthesis of quaternary α-amino acid derivatives using a phenylalanine-derived P-chirogenic diaminophosphine oxide is described. Asymmetric allylic substitution using acyclic β-keto esters with a nitrogen functional group at the α-carbon as prochiral nucleophiles proceeded in the presence of 5 mol % of Pd catalyst, 10 mol % of chiral diaminophosphine oxide 1j, BSA, and appropriate additives, affording the corresponding quaternary α-amino acid derivatives in excellent yield and in up to 92% ee.