296274-10-7

Basic information

• Product Name: ethyl 4-(4-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate
• Synonyms: ethyl 4-(4-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate
• CAS NO: 296274-10-7
• Molecular Formula: C21H24FNO3
• Molecular Weight: 357.4185632
• Mol File: 296274-10-7.mol
• Article Data: 76

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 4-(4-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate(296274-10-7)
• EPA Substance Registry System: ethyl 4-(4-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate(296274-10-7)

Safety Data

• Hazardous Substances Data: 296274-10-7(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 126-81-8 dimedone 
• 105-53-3 diethyl malonate 
• 626-34-6 ethyl aminocrotonate 
• 141-97-9 ethyl acetoacetate 
• 337513-52-7 2,2’?((4?fluorophenyl) methylene) bis (3?hydroxy?5,5?dimethylcyclohex?2?en?1?one) 

Downstream Products

• 1403364-10-2 C₂₁H₂₄FNO₃ 
• 1403364-09-9 C₂₁H₂₄FNO₃ 

Relevant articles and documents

Efficient one-pot synthesis of polyhydroquinoline derivatives through the Hantzsch condensation using IRMOF-3 as heterogeneous and reusable catalyst

A mesoporous Zn-based 2-amino terephthalate metal organic framework (IRMOF-3) catalyst was prepared using the solvothermal method. The synthesized catalyst was characterized by powder X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier tran

Biogenic synthesis of ZnO nanoparticles from Parthenium histerophorus extract and its catalytic activity for building bioactive polyhydroquinolines

Abstract: In the present protocol, biogenic synthesis of ZnO nanoparticles using an aqueous extract of weed, i.e. Parthenium is efficiently carried out. The proficient and operationally simple catalytic application of biogenic ZnO nanoparticle is explored towards a synthesis of pharmaceutically relevant and densely functionalized polyhydroquinolines by condensation of four components viz. aromatic aldehyde, dimedone, ethyl acetoacetate, and ammonium acetate. The synthesized polyhydroquinolines were screened for their antimicrobial activity against bacteria and fungi; some of them exhibit better to excellent activity. The developed protocol is enriched with captivating advantages such as excellent yields, shorter reaction time, recyclable catalyst and constructive use of an aqueous extract of Parthenium for the synthesis of ZnO nanoparticle. Graphical abstract: [Figure not available: see fulltext.]

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