296281-97-5

Upstream product

• 3182-93-2 ethyl 2-amino-3-phenylpropanoate hydrochloride 
• 610-14-0 2-nitrobenzyl chloride 
• 32771-73-6 2(R,S)-(2-amino-benzoylamino)-3-phenyl-propionic acid ethyl ester 
• 1795-96-6 phenylalanine ethyl ester 
• 118-48-9 isatoic anhydride 

Downstream Products

• 389635-24-9 N-{2-[2-(1-ethoxycarbonyl-2-phenyl-ethylcarbamoyl)-phenylcarbamoyl]-phenyl}-succinamic acid ethyl ester 
• 389635-22-7 2-(2-{2-[2-(4-chloro-phenyl)-acetylamino]-benzoylamino}-benzoylamino)-3-phenyl-propionic acid ethyl ester 
• 389635-19-2 2-[2-(2-benzoylamino-benzoylamino)-benzoylamino]-3-phenyl-propionic acid ethyl ester 
• 389635-23-8 3-Phenyl-2-(2-{2-[(E)-(3-phenyl-acryloyl)amino]-benzoylamino}-benzoylamino)-propionic acid ethyl ester 
• 389635-18-1 2-(2-{2-[(1H-indole-2-carbonyl)-amino]-benzoylamino}-benzoylamino)-3-phenyl-propionic acid ethyl ester 
• 389635-20-5 2-{2-[2-(3-methyl-benzoylamino)-benzoylamino]-benzoylamino}-3-phenyl-propionic acid ethyl ester 
• 389635-21-6 3-phenyl-2-[2-(2-phenylacetylamino-benzoylamino)-benzoylamino]-propionic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis of N-terminal substituted anthranilic acid dimer derivatives for evaluation on CCK receptors

A series of new N-substituted anthranilic acid dimer derivatives having a C-terminal Phe residue was synthesized and evaluated for their affinity for CCK receptors. These compounds resulted from a blended approach based firstly on the use of an alternative substructure embedded within asperlicin and secondly on the derivatization of this template with substituents chosen considering the C-terminal primary structure of the endogenous ligand. Although these compounds exhibited a regnylogical-type organization similar to that of CCK-4, they are characterized by about 1000-fold greater affinity for CCK-A receptor than the C-terminal tetrapeptide.

C-terminal anthranoyl-anthranilic acid derivatives and their evaluation on CCK receptors

A series of C-terminal anthranoyl-anthranilic acid derivatives arising from a strict bond disconnection approach of asperlicin were synthesized and examined for their CCK receptor affinities. These compounds represent the second step of our investigation