29636-84-8Relevant academic research and scientific papers
Pd-catalyzed direct arylation of electron-deficient polyfluoroarenes with aryliodine(III) diacetates
Fu, Zhengjiang,Xiong, Qiheng,Zhang, Wenbiao,Li, Zhaojie,Cai, Hu
supporting information, p. 123 - 126 (2015/02/05)
A Pd-catalyzed direct arylation of electron-deficient polyfluoroarenes with readily available aryliodine(III) diacetates was developed with moderate to good yields. The process exhibited good functional tolerance with respect to methyl, methoxy, bromo, chloro, trifluoromethyl, cyano, and aldehyde groups. Mechanistic studies revealed this coupling involved in situ generation of aryl iodide from heating-promoted decomposition of aryliodine(III) diacetate, followed by coupling with polyfluoroarenes substrates to afford the desired products.
Palladium-catalyzed cross-coupling of polyfluoroarenes with simple arenes
Li, Hu,Liu, Jia,Sun, Chang-Liang,Li, Bi-Jie,Shi, Zhang-Jie
supporting information; experimental part, p. 276 - 279 (2011/04/17)
The most efficient method to construct biaryls is the direct dehydrogenative cross-coupling of two different aromatic rings. Such an ideal cross arylation starting from distinct polyfluoroarenes and simple arenes was presented. The selectivity of the cross-coupling was controlled by both of the electronic property of fluoroarenes and steric hindrance of simple arenes. Diisopropyl sulfide was essential to promote the efficacy.
