29636-94-0

Usage

Uses

Used in Organic Synthesis and Chemical Research:
3H-Indolium, 1-(2-hydroxyethyl)-2,3,3-trimethyl-, bromide is used as a reagent for various reactions in organic synthesis and chemical research. Its unique chemical structure and properties make it a valuable component in the development of new compounds and materials.
Used in Textile Industry:
In the textile industry, 3H-Indolium, 1-(2-hydroxyethyl)-2,3,3-trimethyl-, bromide is used as a dye. Its ability to impart color and its stability in various conditions make it a useful component in the production of textiles.
Used in Biological Research:
3H-Indolium, 1-(2-hydroxyethyl)-2,3,3-trimethyl-, bromide is also used as a stain in biological research. Its ability to bind to specific biological molecules allows researchers to visualize and study various cellular structures and processes.
Used in Pharmaceutical Applications:
3H-Indolium, 1-(2-hydroxyethyl)-2,3,3-trimethyl-, bromide has been studied for potential pharmaceutical applications due to its unique chemical structure and properties. Its potential use in the development of new drugs and therapies is an area of ongoing research.

Upstream product

• 1640-39-7 2,3,3-trimethylindoleniune 
• 540-51-2 2-bromoethanol 
• 563-80-4 3-methyl-butan-2-one 
• 54683-96-4 2,3,3-Trimethyl-indolenin 
• 100-63-0 phenylhydrazine 

Downstream Products

• 25952-50-5 1-(β-methacryloxyethyl)-3,3-dimethyl-6'-nitrospiro(indoline-2,2'-<2H>benzopyran) 
• 16111-07-2 2-(3',3'-dimethyl-6-nitro-3'H-spiro[chromene-2,2'-indol]-1'-yl)-ethanol 
• 59335-14-7 10-[2-(4-dimethylaminophenyl)ethylene]-9,9-trimethyl-indolino-[2,1-b]oxazolidine 

Relevant academic research and scientific papers

Application of stimuli-responsive FRET behavior toward cyanide detection in a photo-switchable [2]pseudorotaxane polymer containing the BODIPY donor and the merocyanine acceptor

We have developed a supramolecular (close form) [2]pseudorotaxane polymer containing the green-emissive (λem= 523 nm) BODIPY-based pillar[5]arene host and the non-emissive spiropyran (SP)-based cyano guest (close form), which can be converted t

Magneto-responsive photochromic acrylic copolymer nanoparticles: An investigation into the mutual interactions and photoisomerization kinetics

Photoresponsive and magneto-responsive smart materials have received specific attention. Here, novel bifunctional polyacrylic nanoparticles were prepared via miniemulsion polymerization in which, magnetite nanoparticles (10–15 nm) were resided in the core and poly (methyl methacrylate-co-spiropyran ethyl acrylate) (poly (MMA-co-SPEA)) was located in the shell. Chemical bonding of spiropyran onto the surface of magnetite provided their close vicinity, leading to effective interactions which have not been studied before. The interactions between the excited state of merocyanine (MC) zwitterion from spiropyran (SP) group and magnetic field of the superparamagnetic Fe3O4 NPs were investigated. The results revealed the existence of mutual interactions and successful increment in the absorption intensity (up to 176%) and optical stability, 9% changes in the rate of photoisomerization and increment in the half life time of MC isomers. These were achieved in the presence of magnetite as well as enhancement in the magnetic properties by 10% under UV irradiation at 365 nm. Such synergistic and two-way interactions between magnetic field of the superparamagnetic Fe3O4 NPs and the produced instant dipole moments in MC may offer a new route toward preparation of dual responsive nanocomposite particles for light-triggered magnetic switches, magnetic-triggered photo switches and simultaneous sensing and separation probes.

Unlocking Chemically Encrypted Information Using Three Types of External Stimuli

Encryption is critical to information security; however, existing chemical-based information encryption strategies are still in their infancy. We report here a new approach to chemical encryption involving a supramolecular gel QR (quick response) code wit

Light-Driven Expansion of Spiropyran Hydrogels

The incorporation of molecular switches in organic structures is of great interest in the chemical design of stimuli-responsive materials that mimic the complex functions of living systems. Merocyanine dyes that convert to spiropyran moieties upon exposure to visible light have been extensively studied as they can be incorporated in hydrated covalent networks that will expel water when this conversion occurs and induce a volumetric shrinkage. We report here on a sulfonate-based water-soluble photoswitch that, in contrast to the well-known systems, triggers a volumetric expansion in hydrogels upon exposure to photons. Contraction is in turn observed under dark conditions in a highly reversible manner. The novel behavior of the photoswitch incorporated in the covalent network was predicted by coarse-grained simulations of the system's chemical structure. Using pH control and polymeric structures that differ in lower critical solution temperature, we were able to develop hydrogels with highly tunable volumetric expansion. The novel molecular function of the systems developed here led to materials with the negative phototaxis observed in plants and could expand the potential use of hydrogels as sensors, soft robots, and actuators.

Covalent organic framework material with spiropyrane molecular switch and preparation method and application

The invention provides a covalent organic framework material with a spiropyrane photomolecular switch and a preparation method and application thereof, and belongs to the technical field of luminescent materials and covalent organic framework materials. The preparation method of the covalent organic framework material comprises the following steps: adding BPNA-COF, azido spiropyrane and a catalystinto an organic solvent, mixing, degassing and adding triethylamine; and stirring and reacting to obtain the product, wherein the azido spiropyran is 1-(3-azido ethyl)-1, 3-dihydro-3, 3-dimethyl-6-nitro-spiro [2H-1-benzopyran-2, 2 [2H] indole]. The spiropyrane post-modified on the covalent organic framework material has two active isomers of an open loop and a closed loop and reversible conversion of the two isomers can be realized under irradiation of ultraviolet light and visible light, and the material has excellent light fatigue resistance and has a characteristic response to a hydrochloric acid aqueous solution with the pH value of 3.

Activatable fluorescent probes for hydrolase enzymes based on coumarin-hemicyanine hybrid fluorophores with large Stokes shifts

We show that the equilibrium of intramolecular spirocyclization of coumarin-hemicyanine hybrid fluorophores can be finely tuned by means of chemical modifications. We used this scaffold to develop activatable fluorescent probes with large Stokes shifts for γ-glutamyltranspeptidase and esterase.

Cyanine derivative compound as well as preparation method and application thereof

The invention discloses a cyanine derivative compound as well as a preparation method and application thereof. The compound has a structure as shown in a formula (1). The invention also discloses a preparation method of the compound. The series of compounds can be used as fluorescent markers of mitochondria for living cell imaging analysis or flow cytometry analysis, and the problems of high toxicity, high cost and poor imaging effect of an existing mitochondria fluorescent dye are solved.

Fluorescent dye, preparation method and applications thereof

The invention belongs to the technical field of organic synthesis, and particularly relates to a fluorescent dye, a preparation method and applications thereof, wherein the fluorescent dye has a structural general formula represented by a formula I defined in the specification, X and Y are the same or different O, S, C(CH3)2 or NR6, R2 and R3 are the same or different hydrogen or functional groups, R1, R4, R5 and R6 are all functional groups, and Z is a negative ion. According to the present invention, the fluorescent dye has living cell membrane permeability, can be used for fluorescence imaging of living cell microstructures, and can obtain STED super-resolution fluorescence imaging, laser confocal imaging and other fluorescence imaging of living cells.

Development of a photoswitchable lithium-sensitive probe to analyze nonselective cation channel activity in migrating cancer cells

This is the first work to use a newly designed Li1-selective photoswitchable probe Sabrina Heng Lithium (SHL) in living colon cancer cells to noninvasively monitor cation channel activity in real time by the appearance of lithium hot spots dete

Photooxidation of oxazolidine molecular switches: Uncovering an intramolecular ionization facilitated cyclization process

Photooxidation of oxazoline (OXA) molecular switches through media-induced intramolecular ionization is reported. The formation of the photooxidation product occurs by attack of the flexible donor group (-CH2CH2OH) to the adjacent CC with 1O2 as the oxidant. The novel seven-membered ring sub-structure of the photooxidation product was inferred by HRMS, IR and 1H NMR spectroscopy. Additionally, acid released from solvent photolysis was found to affect the product formation and efficiency of the photooxidation.