296766-66-0

Basic information

• Product Name: N,N'-methylene[(2S,4R,5R)-4-methyl-1,3-dioxan-2,5-diyl]-[(2'S,5'R)-1,3-dioxacyclooctan-2,5-diyl]bisbenzamide
• Synonyms: N,N'-methylene[(2S,4R,5R)-4-methyl-1,3-dioxan-2,5-diyl]-[(2'S,5'R)-1,3-dioxacyclooctan-2,5-diyl]bisbenzamide
• CAS NO: 296766-66-0
• Molecular Weight: 454.523
• Mol File: 296766-66-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N'-methylene[(2S,4R,5R)-4-methyl-1,3-dioxan-2,5-diyl]-[(2'S,5'R)-1,3-dioxacyclooctan-2,5-diyl]bisbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-methylene[(2S,4R,5R)-4-methyl-1,3-dioxan-2,5-diyl]-[(2'S,5'R)-1,3-dioxacyclooctan-2,5-diyl]bisbenzamide(296766-66-0)
• EPA Substance Registry System: N,N'-methylene[(2S,4R,5R)-4-methyl-1,3-dioxan-2,5-diyl]-[(2'S,5'R)-1,3-dioxacyclooctan-2,5-diyl]bisbenzamide(296766-66-0)

Safety Data

• Hazardous Substances Data: 296766-66-0(Hazardous Substances Data)

Upstream product

• 296766-50-2 [(2S,4R,5R)-N-2-(2,2-dimethoxyethyl)-4-methyl-1,3-dioxan-5-yl]benzamide 
• 1245643-19-9 (1S)-N-[3-hydroxy-1-(hydroxymethyl)propyl]benzamide 
• 398118-87-1 (2S,4R,5R)-N-(2-formylmethyl-4-methyl-1,3-dioxane-5-yl)benzamide 
• 296766-73-9 (1S)-N-[3-hydroxy-1-(hydroxymethyl)propyl]benzamide 

Relevant articles and documents

Diasteroselective cyclizations with enantiopure malonaldehyde monocycloacetals

The synthesis of a series of enantiopure malonaldehyde monocycloacetals is described. Treatment of 8b with L-tryptophan methyl ester, 5-methoxytryptamine, and tryptamine, respectively, in the Pictet-Spengler condensation gave the corresponding enantiomerically pure key precursors 1-3 and 17-21 in only two steps. Using a chiral amino-diol successfully realized the kinetic resolution of racemic carbolines 23 and 24.