296776-78-8

Basic information

• Product Name: (S)-3-(m-tolyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide
• Synonyms: (S)-3-(m-tolyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide
• CAS NO: 296776-78-8
• Molecular Weight: 259.329
• Mol File: 296776-78-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (S)-3-(m-tolyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(m-tolyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide(296776-78-8)
• EPA Substance Registry System: (S)-3-(m-tolyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide(296776-78-8)

Safety Data

• Hazardous Substances Data: 296776-78-8(Hazardous Substances Data)

Upstream product

• 28987-79-3 m-tolylmagnesium bromide 
• 81-07-2 saccharin 
• 296776-75-5 3-(3-methylphenyl)-1,2-benzisothiazole 1,1-dioxide 
• 620-23-5 m-tolyl aldehyde 

Relevant articles and documents

Pd/Zn(OTf)2 Co-Catalyzed Asymmetric Hydrogenation of Imines under Normal Pressure of Hydrogen

An efficient method for the asymmetric hydrogenation of cyclic and acyclic N-sulfonylimines co-catalyzed by Pd/Zn(OTf)2 using hydrogen gas under ambient pressure was developed. The methodology offers an easy access to generate chiral sulfonylam

Synthesis of chiral sultams via palladium-catalyzed intramolecular asymmetric reductive amination

A novel palladium-catalyzed intramolecular reductive amination of ketones with weakly nucleophilic sulfonamides has been developed in the presence of a Br?nsted acid, giving a wide range of chiral γ-, δ-, and ε-sultams in high yields and up to 99% of enan

Method for synthesizing chiral amine through palladium catalyzed asymmetric hydrogenolysis of racemic oxazirine

A catalysis system used in a method for synthesizing chiral amine through palladium catalyzed asymmetric hydrogenolysis of racemic oxazirine is a chiral diphosphine complex of palladium. The racemic substituted oxazirine is hydrogenolyzed to obtain corresponding chiral sulfonamide, and the enantiomeric excess can reach 99%. The method has the advantages of simple, practical and easy operation, commercially available catalyst and mild reaction conditions. The method for synthesizing the chiral sulfonamide through asymmetric hydrogenolysis also has the advantages of high antipodal selectivity, good yield, environmentally-friendly and atomically-economic reaction, and environmental protection.