297135-61-6

Upstream product

• 121352-88-3 [(2R,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxiranyl]-methanol 
• 152426-82-9 (3S)-3,5-bis-(tert-butyldimethylsilyloxy)-2,2-dimethylpentanal 
• 152426-87-4 (2R,6S)-2-Benzyloxymethyl-6-iodomethyl-4,4-dimethoxy-tetrahydro-pyran 
• 152426-86-3 ((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-yl)-methanol 
• 152426-83-0 2-[(S)-2,4-Bis-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-butyl]-[1,3]dithiane 
• 152426-85-2 (2R,6S)-2-Benzyloxymethyl-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4,4-dimethoxy-tetrahydro-pyran 
• 187527-29-3 [(S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-pentyloxymethyl]-benzene 
• 152426-89-6 (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentan-1-ol 
• 152426-88-5 (2R,6S)-2-Benzyloxymethyl-6-{2-[(S)-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-butyl]-[1,3]dithian-2-ylmethyl}-4,4-dimethoxy-tetrahydro-pyran 
• 152426-84-1 (2S,6S)-2-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-vinyl-tetrahydro-pyran-4-one 
• 187527-30-6 (3S)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2,2-dimethylpentan-1-ol 
• 152426-81-8 (3S)-1-benzyloxy-2,2-dimethylpentane-3,5-diol 
• 105367-62-2 1'(R),6-Dimethyl-4'(S)-isopropyl-4-oxospiro--dioxin> 
• 152426-90-9 (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal 

Downstream Products

• 152426-92-1 (5S,7S)-8-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-8-methyl-3-oxo-nonanoic acid ethyl ester 
• 297135-63-8 (5S,7S)-8-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-8-methyl-3-oxo-nonanoic acid 2-trimethylsilanyl-ethyl ester 
• 152426-93-2 {(4R,6R)-6-[(S)-3-[2-((2S,6R)-6-Benzyloxymethyl-4-oxo-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-2-(tert-butyl-dimethyl-silanyloxy)-3-methyl-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester 
• 297135-65-0 4-[6-(6-benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-4-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-5,5-dimethyl-tetrahydro-pyran-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-butyric acid 2-trimethylsilanyl-ethyl ester 
• 297135-64-9 (3R,5R,7S)-8-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-7-(tert-butyl-dimethyl-silanyloxy)-3,5-dihydroxy-8-methyl-nonanoic acid 2-trimethylsilanyl-ethyl ester 

Relevant academic research and scientific papers

Synthetic studies on bryostatins, antineoplastic metabolites: Convergent synthesis of the C1-C16 fragment shared by all of the bryostatin family

The C1-C16 fragment of bryostatins could successfully be synthesized by tandem connection of the appropriate three fragments and effective introduction of the α,β-unsaturated esters at the C13 position.