152426-85-2

Upstream product

• 81277-28-3 (2S,4'R)-2-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-2,3-dihydro-4H-pyran-4-one 
• 100-39-0 benzyl bromide 
• 152426-84-1 (2S,6S)-2-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-vinyl-tetrahydro-pyran-4-one 

Downstream Products

• 297135-61-6 (6R,7S,10R)-4-[(2S,4S)-5-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-4-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-5-methyl-hexyl]-7-isopropyl-10-methyl-1,5-dioxa-spiro[5.5]undec-3-en-2-one 
• 152426-93-2 {(4R,6R)-6-[(S)-3-[2-((2S,6R)-6-Benzyloxymethyl-4-oxo-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-2-(tert-butyl-dimethyl-silanyloxy)-3-methyl-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester 
• 152426-92-1 (5S,7S)-8-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-8-methyl-3-oxo-nonanoic acid ethyl ester 
• 152426-88-5 (2R,6S)-2-Benzyloxymethyl-6-{2-[(S)-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-butyl]-[1,3]dithian-2-ylmethyl}-4,4-dimethoxy-tetrahydro-pyran 
• 152426-90-9 (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal 
• 152426-89-6 (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentan-1-ol 
• 152426-86-3 ((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-yl)-methanol 
• 152426-87-4 (2R,6S)-2-Benzyloxymethyl-6-iodomethyl-4,4-dimethoxy-tetrahydro-pyran 

Relevant academic research and scientific papers

Synthetic studies on bryostatins, antineoplastic metabolites: Convergent synthesis of the C1-C16 fragment shared by all of the bryostatin family

The C1-C16 fragment of bryostatins could successfully be synthesized by tandem connection of the appropriate three fragments and effective introduction of the α,β-unsaturated esters at the C13 position.