29778-31-2Relevant articles and documents
Palladium/copper-cocatalyzed decarbonylative alkynylation of acyl fluorides with alkynylsilanes: Synthesis of unsymmetrical diarylethynes
Chen, Qiang,Fu, Liyan,Nishihara, Yasushi
supporting information, p. 7977 - 7980 (2020/09/09)
Palladium/copper-cocatalyzed decarbonylative alkynylation of acyl fluorides with alkynylsilanes is described. This reaction not only effectively inhibits the formation of undesired homocoupled products by avoiding the addition of a base, but also exhibits a wide substrate scope to provide a general access to diverse unsymmetrical diarylethynes.
Sonogashira cross-coupling reaction catalysed by mixed NHC-Pd-PPh3 complexes under copper free conditions
Touj, Nedra,Ya?ar, Sedat,?zdemir, Nam?k,Hamdi, Naceur,?zdemir, ?smail
, p. 59 - 71 (2018/02/27)
Mixed NHC–Pd–PPh3 complexes with a methoxyethyl-substituted N-heterocyclic carbene (NHC) were synthesised and characterised by NMR, HRMS, elemental analysis and X-ray crystallography for complex 3b. These complexes were applied to Sonogashira c
Synthesis of Trisubstituted Acrylic Acids through Nickel-Catalyzed Carbomagnesiation of Alkynes and Carbon Dioxide Fixation
Hung, Chen-Hsun,Santhoshkumar, Rajagopal,Chang, Yu-Che,Cheng, Chien-Hong
supporting information, p. 6924 - 6928 (2018/11/23)
A nickel-catalyzed synthesis of trisubstituted acrylic acids from alkynes, Grignard reagents, and CO2 is reported. The reaction proceeds through carbomagnesiation of the alkyne with Grignard reagent followed by carboxylation with CO2 under mild reaction conditions in short time. Various unsymmetrical alkynes were transformed into the corresponding acid products in good yields with high stereoselectivity.