2985-57-1

Usage

Uses

Used in Chemical Production Industry:
4-Decylphenol is used as an intermediate for the synthesis of antioxidants, which are essential in preventing the oxidation of materials and extending the shelf life of products. It plays a crucial role in the development of lubricating oil additives, enhancing the performance and longevity of lubricants. Additionally, it serves as a precursor in the creation of surfactants, which are vital for stabilizing and emulsifying various products.
Despite its applications, the endocrine-disrupting properties of 4-decylphenol have led to its association with reproductive and developmental toxicity, as well as potential carcinogenic effects. Consequently, there is a growing movement to regulate and minimize its use in consumer products and industrial processes to mitigate the risks to human health and the environment.

InChI:InChI=1/C16H26O/c1-2-3-4-5-6-7-8-9-10-15-11-13-16(17)14-12-15/h11-14,17H,2-10H2,1H3

Upstream product

• 14353-77-6 1-(4-hydroxy-phenyl)-decan-1-one 
• 848737-04-2 1-n-decyl-4-methoxybenzene 
• 100-66-3 methoxybenzene 
• 108-95-2 phenol 
• 101741-01-9 1-(4-methoxyphenyl)decan-1-one 
• 2050-77-3 Iododecane 
• 108-86-1 bromobenzene 
• 14353-75-4 phenyl decanoate 
• 334-48-5 1-decanoic acid 
• 112-13-0 n-decanoyl chloride 
• 104-72-3 decylbenzene 

Downstream Products

• 14353-82-3 4-decylphenoxyacetic acid 
• 94435-57-1 3-(4-decyl-phenoxy)-propane-1,2-diol 
• 103350-40-9 3,4-Dichlor-benzyl-thiocarbamidsaeure-<4-decyl-phenyl-ester> 
• 1026078-36-3 2-[(S)-2-(4-Decyl-phenoxy)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-tetrahydro-pyran 
• 160582-39-8 (S)-ethyl 2-acetoxy-(4-decylphenoxy)butanoate 
• 1162025-31-1 bis(2-hydroxy-5-n-decylphenyl)methane 
• 77635-20-2 5-decylsalicylaldehyde 
• 16260-14-3 4-Decyl-2-nitro-phenol 
• 101443-38-3 (Ξ)-4-Decyl-cyclohexanol 
• 669091-82-1 2-Amino-4-decyl-phenol 
• 144381-64-6 [2-(6,7,9,10,12,13,15,16,18,19-Decahydro-5,8,11,14,17,20-hexaoxa-benzocyclooctadecen-12-ylmethoxy)-5-decyl-phenyl]-phosphonic acid diethyl ester 
• 144381-65-7 [2-(6,7,9,10,12,13,15,16,18,19-Decahydro-5,8,11,14,17,20-hexaoxa-benzocyclooctadecen-12-ylmethoxy)-5-decyl-phenyl]-phosphonic acid monoethyl ester 

Relevant academic research and scientific papers

Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives

C14 alkyl benzoate ABG001, derived from naturally occurring gentisides, was reported to exhibit neurotrophic activity which is similar to NGF (Nerve Growth Factor). In this research, ABG001 was modified by the strategy of isosteric replacement and conformational restriction with the purpose of improving the bioactivity. The cellular neurotrophic activity of those ABG001 derivatives were evaluated, among which 3-hydroxyquinolin-2-(1H)-one A3 and 4-decylphenol ester B7 displayed much better neurotrophic activity compared with ABG001, which highlights the potential of those novel scaffolds for future neurotrophic agent development.

Synthesis and critical micelle concentration of a series of gemini alkylphenol polyoxyethylene nonionic surfactants

A series of gemini n-alkylphenol polyoxyethylene surfactants (GAP) were successfully synthesized and their molecular structure were confirmed by NMR and FTIR spectrum. Using the same synthesis route, a Gemini nonylphenol polyoxyethylene surfactant (GNP) was synthesized using an industrial nonylphenol product and paraformaldehyde, and its molecular structure was also characterized by 1H-NMR and FTIR spectra. The optimal reaction conditions were established. The critical micelle concentration (CMC) values of GAP were determined by means of Wilhelmy plate method and steady-state fluorescence probe method. The experimental results show how the lengths of the hydrophilic polyoxyethylene chain and the hydrophobic tail alter the CMC values. The CMC values of the GAP are found to be much lower than those of corresponding conventional single tail nonionic surfactants of the polyethoxylated alkylphenol type, which indicates that the gemini species exhibit a better surface activity. AOCS 2011.

Tilt Angle Variation as a Function of Chain Length and Temperature in the Smectic C Phases of p,Alkoxyphenyl-p,Alkoxybenzoates

The variation of the tilt angle with temperature in the smectic C phase has generally been shown to be non-existent or very slow for compounds or mixtures with the nematic-smectic C transition, while in the case of systems with the smectic A-smectic C transition, a relation between the steepness of this variation, near the transition, and the width of the smectic A domain has been observed.In this work, the variation of tilt angle in the smectic C phase is described for p-alkoxyphenyl-p-alkoxybenzoate homologous series, for which the evolution of polymorphism can be controlled systematically, by varying stepwise the length of the aliphatic chains, and for which large domains can be obtained for each type of phase sequence, nematic-, smectic A- and isotropic-smectic C.After completing the discussion made previously on the incidence of chain length on polymorphism, we confirm that the variation of tilt angle with temperature is slowest for compounds with intermediate chain lengths corresponding to the largest smectic A temperature range; this variation becomes continuously steeper when the smectic A domain becomes narrow.In addition, we show that the same description can be extended to the other types of phase sequences, by using the hypothesis of a virtual smectic A-smectic C transition above the observed nematic- or isotropic-smectic C transition.In fact, short chain lengths for homologues with a nematic/smectic C transition, or long chain lengths for homologues with an isotropic/smectic C transition, lead to an increase of the tilt angle at the phase transition and to a decrease of the amplitude of its variation with temperature; in our description, this behaviour corresponds to an increase of the temperature range between the real and virtual transitions.As a consequence, the homologues with very short and very long chain lengths show a quasi temperature-independent tilt angle, while the other homologues present a tilt angle variation similar to that observed for compounds exhibiting a smectic C/smectic A transition.This feature indicates that there is no need to distinguish between different types of smectic C phase.

RECHERCHES SUR LES SUBSTANCES MESOGENES-VIII; PREPARATION ET PROPERTIES MESOMORPHES DE SERIES ISOMETRIQUES

The synthesis and the mesomorphic properties of various series of isometric mesogenic compounds are described.It is confirmed that isometric mesogenic molecules may be nematogenic and/or smectogenic according to the position of the polar rigid core.