29898-72-4Relevant academic research and scientific papers
Simple practical method for synthesis of trisubstituted imidazoles: an efficient copper catalyzed multicomponent reaction
Kadu, Vikas D.,Khadul, Siddheshwar P.,Kothe, Gokul J.,Mali, Ganesh A.
, p. 21955 - 21963 (2021/07/02)
A rapid practical process has been developed for synthesis of 2,4,5-trisubstituted-imidazoles in excellent yields up to 95% from readily available starting materials. In this CuI catalyzed synthesis, trisubstituted imidazoles were afforded in short reaction times, wherein the substrate scope is well explored with benzoin as well as benzil reacting with different aldehydes in the presence of ammonium acetate as the nitrogen source.
Evidence for the Formation of 1,2-Dioxetane as a High-Energy Intermediate and Possible Chemiexcitation Pathways in the Chemiluminescence of Lophine Peroxides
Boaro, Andreia,Reis, Roberta Albino,Silva, Carolina Santana,Melo, Diêgo Ulysses,Pinto, Alexander Garreta Gon?alves Costa,Bartoloni, Fernando Heering
, p. 6633 - 6647 (2021/05/29)
A kinetic study of the chemiluminescent (CL) reaction mechanism of lophine-derived hydroperoxides and silylperoxides induced by a base and fluoride, respectively, provided evidence for the formation of a 1,2-dioxetane as a high-energy intermediate (HEI) o
Intramolecular charge transfer ampholytes with water-induced pendulum-type fluorescence variation
Dong, Xiao-Bin,Chen, Ling,Pan, Mei,Huang, Wen-Jie,Xiang, Hua,Wang, Hai-Ping,Mo, Zong-Wen,Ye, Jia-Wen,Zhang, Kun,Chen, Xiao-Ming
supporting information, p. 10702 - 10705 (2020/10/05)
Triphenylimidazole-based ampholytes with intramolecular charge transfer were designed with the introduction of carboxyl groups. In solution, the synergistic solvent and ionization effects on the ampholytes led to a unique pendulum-type fluorescence variation during the water content increasing process. Among them, 4-(4,5-bis(4-hydroxyphenyl)-1H-imidazol-2-yl)benzoic acid showed the most prominent three-step fluorescence switching property.
BORONIC ACID-BASED COMPOUND AND METHOD FOR PREPARATION THEREOF
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, (2019/01/04)
The present invention relates to a boronic acid-based compound and a preparation method thereof. More specifically, the present invention provides: a derivative containing boronic acid and imidazole obtained by substituting various functional groups during a synthesizing process of a boronic acid-based compound; and a preparation method of the derivative in high yield without using an oxidant.COPYRIGHT KIPO 2018
Cu(II) immobilized on guanidinated epibromohydrin-functionalized γ-Fe2O3@TiO2 (γ-Fe2O3@TiO2-EG-Cu(II)): A highly efficient magnetically separable heterogeneous nanocatalyst for one-pot synthesis of highly substituted imidazoles
Nejatianfar, Mahdi,Akhlaghinia, Batool,Jahanshahi, Roya
, (2017/10/23)
A simple, efficient and eco-friendly procedure has been developed using Cu(II) immobilized on guanidinated epibromohydrin-functionalized γ-Fe2O3@TiO2 (γ-Fe2O3@TiO2-EG-Cu(II)) for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles, via the condensation reactions of various aldehydes with benzil and ammonium acetate or ammonium acetate and amines, under solvent-free conditions. High-resolution transmission electron microscopy analysis of this catalyst clearly affirmed the formation of a γ-Fe2O3 core and a TiO2 shell, with mean sizes of about 10–20 and 5–10?nm, respectively. These data were in very good agreement with X-ray crystallographic measurements (13 and 7?nm). Moreover, magnetization measurements revealed that both γ-Fe2O3@TiO2 and γ-Fe2O3@TiO2-EG-Cu(II) had superparamagnetic behaviour with saturation magnetization of 23.79 and 22.12?emu g?1, respectively. γ-Fe2O3@TiO2-EG-Cu(II) was found to be a green and highly efficient nanocatalyst, which could be easily handled, recovered and reused several times without significant loss of its activity. The scope of the presented methodology is quite broad; a variety of aldehydes as well as amines have been shown to be viable substrates. A mechanism for the cyclocondensation reaction has also been proposed.
2-hydroxyethylammonium formate ionic liquid grafted magnetic nanoparticle as a novel heterogeneous catalyst for the synthesis of substituted imidazoles
Rajabzadeh, Maryam,Eshghi, Hossein,Khalifeh, Reza,Bakavoli, Mehdi
, (2017/10/09)
Catalytic one-pot condensation of benzil, aldehyde and ammonium acetate have been successfully carried out using 2-hydroxyethylammonium formate (HEAF) grafted on a magnetic nanoparticles as a new heterogeneous catalyst. The as-prepared catalyst was charac
Simple, Efficient, and Convenient One-Pot Synthesis of Imidazole Derivatives in the Presence of Nanosilica-supported Imidazolium Ionic Liquid as a Catalyst
Alinezhad, Heshmatollah,Alinezhad, Vajiheh,Mohseni Tavakkoli, Sahar
, p. 385 - 389 (2017/04/24)
An efficient and simple synthesis of 2,4,5-trisubstituted imidazoles is achieved by three-component cyclocondensation of benzil, aldehyde, and ammonium acetate by using nanosilica-supported imidazolium ionic liquid as a catalyst under solvent-free conditions. The key advantages of this process are high to excellent yields, short reaction time, easy work-up, and the reusability of the catalyst.
An Efficient and Green Synthesis of Imidazoles Using Natural Organic Acids as Promoter under Solvent-Free Condition
Dhawale, Kiran D.,Thorat, Nitin M.,Patil, Limbraj R.
, p. 1702 - 1712 (2017/06/27)
An efficient and eco-friendly synthesis of imidazoles, promoted by naturally occurring acids, via condensation of benzil, aldehyde and ammonium acetate using conventional and microwave heating under solvent-free condition is described. Reactions under mic
Isocyanurate-based periodic mesoporous organosilica (PMO-ICS): A highly efficient and recoverable nanocatalyst for the one-pot synthesis of substituted imidazoles and benzimidazoles
Dekamin, Mohammad G.,Arefi, Elham,Yaghoubi, Amene
, p. 86982 - 86988 (2016/10/19)
Isocyanurate bridging periodic mesoporous organosilica (PMO-ICS) was shown to be a highly active and efficient recyclable catalyst for the three-component synthesis of imidazole derivatives from benzoin, different aldehydes and ammonium acetate under mild reaction conditions in short reaction times and good to excellent yields in EtOH. Also, benzimidazole derivatives were efficiently prepared from o-phenylenediamine and different aldehydes in the presence of PMO-ICS. Moreover, the catalyst was also recovered and reused at least four times without a significant decrease in its activity. The PMO-ICS catalyst was characterized by Fourier transformer infrared (FTIR) spectroscopy, thermogravimetry analysis (TGA), powder X-ray diffraction (XRD) and nitrogen adsorption-desorption isotherm (NADI) techniques as well as field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). Compared to the classical methodologies, this method illustrated significant advantages including low loading of the catalyst, avoiding the use of toxic transition metals or reactive reagents for modification of the catalytic activity, short reaction times, high to excellent yields, easy separation and purification of the products, and reusability of the catalyst.
