299403-91-1

Upstream product

• 65-85-0 benzoic acid 
• 299403-89-7 (2R,4aS,6R,7R,9aR)-2-Allyl-6-((Z)-pent-2-en-4-ynyl)-4a,6,7,9a-tetrahydro-2H-1,5-dioxa-benzocyclohepten-7-ol 
• 299403-76-2 (2R,3S,6R)-6-Allyl-3-(1-ethoxy-ethoxy)-2-prop-2-ynyl-3,6-dihydro-2H-pyran 
• 299403-83-1 (1aS,2aR,4R,6aS,8R,8aS)-4-Allyl-1a-triethylsilanyl-8-((Z)-5-triisopropylsilanyl-pent-2-en-4-ynyl)-2,2a,4,6a,8,8a-hexahydro-1aH-1,3,7-trioxa-benzo[a]cyclopropa[d]cycloheptene 
• 1026611-82-4 {(2R,4aS,6R,9aR)-2-Allyl-6-[2-(4-methoxy-benzyloxy)-ethyl]-4a,6,9,9a-tetrahydro-2H-1,5-dioxa-benzocyclohepten-8-yl}-triethyl-silane 
• 299403-84-2 (2R,4aS,6R,7R,9aR)-2-Allyl-6-((Z)-5-triisopropylsilanyl-pent-2-en-4-ynyl)-4a,6,7,9a-tetrahydro-2H-1,5-dioxa-benzocyclohepten-7-ol 
• 299403-77-3 (2R,3S,6R)-6-Allyl-2-[4-hydroxy-6-(4-methoxy-benzyloxy)-hex-2-ynyl]-3,6-dihydro-2H-pyran-3-ol 
• 299403-80-8 ((2R,4aS,6R,9aR)-2-Allyl-8-triethylsilanyl-4a,6,9,9a-tetrahydro-2H-1,5-dioxa-benzocyclohepten-6-yl)-acetic acid 
• 299403-82-0 ((1aS,2aR,4R,6aS,8R,8aS)-4-Allyl-1a-triethylsilanyl-2,2a,4,6a,8,8a-hexahydro-1aH-1,3,7-trioxa-benzo[a]cyclopropa[d]cyclohepten-8-yl)-acetaldehyde 
• 299403-78-4 2-((2R,4aS,6R,9aR)-2-Allyl-8-triethylsilanyl-4a,6,9,9a-tetrahydro-2H-1,5-dioxa-benzocyclohepten-6-yl)-ethanol 

Relevant academic research and scientific papers

Acetylene cobalt complex and vinylsilane strategy in the synthesis of ciguatoxin (D)EF analog

A synthetic route to the (D)EF analog of ciguatoxin has been explored through acetylene cobalt complex and vinylsilane strategy. The central reactions in the synthesis are: (i) ether ring formation mediated by acetylene cobalt complex and (ii) decomplexation of the endo-acetylene cobalt complexes to vinylsilanes or olefins. Unusual rearrangement of epoxy-silane to allylic alcohol is also described. (C) 2000 Elsevier Science Ltd.