29947-07-7Relevant academic research and scientific papers
Preparation of 2-BF3-substituted 1,3-dienes and their Diels-Alder/cross-coupling reactions
De, Subhasis,Welker, Mark E.
, p. 2481 - 2484 (2005)
(Chemical Equation Presented) 2-BF3-substituted 1,3-butadienes with potassium and tetrabutylammonium counterions have been prepared in gram quantities from chloroprene via a simple synthetic procedure. The potassium salt of this new main group element substituted diene has been characterized by 1H, 13C, 11B, and 19F NMR. Diels-Alder reactions of these dienes with ethyl acrylate and methyl vinyl ketone are reported, as well as subsequent Pd-catalyzed cross-coupling reactions of those Diels-Alder adducts.
1,7-octadiene-assisted tandem multicomponent cross-enyne metathesis (CEYM)-diels-alder reactions: A useful alternative to Mori's conditions
Fustero, Santos,Bello, Paula,Miro, Javier,Simon, Antonio,Del Pozo, Carlos
experimental part, p. 10991 - 10997 (2012/09/25)
The use of 1,7-octadiene as an in situ source of ethylene led us to develop a novel multicomponent tandem cross-enyne metathesis (CEYM)-Diels-Alder reaction. The process can be considered a relay metathesis, in which the ethylene liberated in the ring-closing metathesis (RCM) of 1,7-octadiene initiates the tandem sequence. Aliphatic, aromatic, and fluorinated alkynes and several dienophiles are compatible with the process, which is particularly efficient with aromatic alkynes. This methodology constitutes a useful variant of Mori's conditions in CEYM-related reactions. El empleo de 1,7-octadieno como una fuente in situ de etileno nos ha permitido desarrollar un nuevo proceso tandem multicomponente metatesis cruzada de enino-reaccion de Diels-Alder. El proceso puede considerarse como una metatesis por relevos, donde el etileno liberado en la metatesis con cierre de anillo del 1,7-octadieno inicia la secuencia tandem. Alquinos alifaticos, aromaticos y fluorados y varios dienofilos son compatibles con el proceso, que es particularmente eficiente con alquinos aromaticos. Esta metodologia constituye una variante stil de las condiciones desarrolladas por Mori en reacciones de metatesis cruzada de eninos. Ruthenium catalysis: A new, multicomponent, tandem cross-enyne metathesis (CEYM)-Diels-Alder reaction that is mediated by 1,7-octadiene is described. The ethylene liberated in the ring-closing metathesis of this diene initiates the enyne metathesis and, in the presence of a dienophile, the tandem process takes place in an efficient manner (see scheme). Copyright
ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES
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, (2011/10/13)
The present invention is concerned with aryl-cyclohexyl-tetraazabenzo[e]azulenes of formula I wherein R1, R2 and R3 are as described herein. The invention further provides methods for the manufacture of such compounds and
ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES
-
, (2011/10/13)
The present invention is concerned with aryl-cyclohexyl-tetraazabenzo[e]azulenes of formula I, wherein R1, R2 and R3 are as described herein. The compounds according to the invention act as Via receptor modulators, and in
Preparation and Diels-Alder/cross coupling reactions of a 2-diethanolaminoboron-substituted 1,3-diene
Wang, Liqiong,Day, Cynthia S.,Wright, Marcus W.,Welker, Mark E.
supporting information; experimental part, (2010/04/22)
A 2-diethanolamine boronyl substituted 1,3-diene has been synthesized in high yield and characterized spectroscopically as well as by X-ray crystallography. This diene has then subsequently been used in a number of fast, high yielding Diels-Alder/cross co
Preparation of 2-silicon-substituted 1,3-dienes and their diels-alder/cross-coupling reactions
Pidaparthi, Ramakrishna R.,Junker, Christopher S.,Welker, Mark E.,Day, Cynthia S.,Wright, Marcus W.
experimental part, p. 8290 - 8297 (2010/02/17)
(Chemical Equation Presented) 2-Triethoxysilyl-substituted 1,3-butadiene has been prepared in 30-g quantities from chloroprene via a simple synthetic procedure. Silatrane- and catechol-substituted analogues of this main group element substituted diene wer
