29973-97-5

Usage

Organic compound

Consists of a benzyl group attached to an amine group

Form

Exists as a hydrochloride salt

Uses

Commonly used in medicinal chemistry and pharmaceutical research for the development of potential drugs and treatments

Applications

May have applications in organic synthesis and chemical reactions

Stability and solubility

The hydrochloride salt form allows for increased stability and solubility in aqueous solutions, making it easier to work with in laboratory settings

Versatility and importance

Considered a versatile and important chemical compound with various potential applications in the science and medical fields.

Upstream product

• 38449-59-1 2-(3-hydroxyphenyl)ethylamine hydrobromide 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 132513-29-2 tert-butyl {2-[3-(benzyloxy)phenyl]ethyl}carbamate 
• 129150-68-1 N-(t-butoxycarbonyl)-2-(3-hydroxyphenyl)-ethylamine 
• 588-05-6 m-tyramine 
• 20967-96-8 2-(3-benzyloxyphenyl)acetonitrile 
• 24550-32-1 1-(benzyloxy)-3-(2-nitrovinyl)benzene 

Downstream Products

• 132513-29-2 tert-butyl {2-[3-(benzyloxy)phenyl]ethyl}carbamate 
• 637773-79-6 (E)-N-(3-benzyloxyphenethyl)-3-(pyridin-3-yl)-2-propenamide 
• 1415684-09-1 (2S,3R,3aS,12bR)-1,2,3,3a,4,5,7,8-octahydro-10-benzyloxy-2-methyl-3-nitromethyl-5-oxo-cyclopenta[2,3]pyrrolo[2,1-a]isoquinoline 
• 1415684-10-4 (2S,3R,3aS,12bR)-1,2,3,3a,4,5,7,8-octahydro-10-benzyloxy-2-methyl-5-oxo-cyclopenta[2,3]pyrrolo[2,1-a]isoquinoline-3-carboxylic acid 
• 1415684-11-5 methyl ester (2S,3R,3aS,12bR)-1,2,3,3a,4,5,7,8-octahydro-10-benzyloxy-2-methyl-5-oxo-cyclopenta[2,3]pyrrolo[2,1-a]isoquinoline-3-carboxylic acid 
• 129150-68-1 N-(t-butoxycarbonyl)-2-(3-hydroxyphenyl)-ethylamine 
• 1092977-06-4 NW-3509 
• 1092977-45-1 2-(2-(3-butoxyphenyl)-N-tert-butoxycarbonylethylamino)-N,N-dimethylthioacetamide 
• 1092977-08-6 2-(2-(3-butoxyphenyl)-N-tert-butoxycarbonylethylamino)-N,N-dimethylacetamide 
• 1092977-28-0 2-(2-(3-butoxyphenyl)-N-tert-butoxycarbonylethylamino)-N,N-dimethylpropanamide 
• 1092977-07-5 2-(3-butoxyphenyl)-N-tert-butoxycarbonylethylamine 
• 1443827-78-8 N-(3-(benzyloxy)phenylethyl)-2-chloroacetamide 
• 1443827-79-9 N-(3-(benzyloxy)phenethyl)-2-(4-methoxyphenoxy)acetamide 
• 1443828-02-1 6-(benzyloxy)-1-((4-methoxyphenoxy)methyl)-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Diverse alkaloid-like structures from a common building block

A wealth of unique enantiopure polycyclic alkaloid-like scaffolds can be prepared on a multigram scale in only a few steps from a common, commercially available intermediate. The attached nitromethyl group can then be used to construct highly diverse func

SYNTHESIS OF POLYCYCLIC ALKALOIDS

Disclosed embodiments concern polycyclic alkaloid compounds and methods for their use and synthesis. Particular embodiments concern polycyclic alkaloids having a fused, six-membered ring, while other embodiments concern polycyclic alkaloids having a fused

Synthesis and structure activity relationship of tetrahydroisoquinoline- based potentiators of GluN2C and GluN2D containing N-Methyl-D-aspartate receptors

We describe here the synthesis and evaluation of a series of tetrahydroisoquinolines that show subunit-selective potentiation of NMDA receptors containing the GluN2C or GluN2D subunits. Bischler-Napieralski conditions were employed in the key step for the

MACROCYCLE DERIVATIVES USEFUL AS INHIBITORS OF beta-SECRETASE (BACE)

The present invention is directed to macrocycle derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.

Heteroaryl and benzyl amide compounds

Compounds of formula I wherein R1, R2, R4, R5, A, B, D and n are as defined, and pharmaceutically acceptable salts thereof, processes for their preparation, their use as pharmaceuticals and pharmaceutical compositions comprising them.

Indole, indazole and indoline derivatives as CETP inhibitors

The present invention relates to compounds of formula (I): wherein —X—Y—, R1 to R11 and n are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are mediated by CETP inhibitors.