2998-23-4

Usage

Uses

Used in Organic Synthesis:
N-Pentyl Acrylate is used as an intermediate in organic synthesis for the production of various chemical compounds. Its reactivity and functional groups make it a versatile building block in the synthesis of a wide range of organic molecules.
Used in Copolymerization:
As a monomer, N-Pentyl Acrylate is used in copolymerization to produce polymers with specific properties. The incorporation of N-Pentyl Acrylate into copolymers can modify their characteristics, such as flexibility, toughness, and chemical resistance, making them suitable for various applications.
Used in Coatings Industry:
N-Pentyl Acrylate is used as a component in the formulation of coatings, such as paints and varnishes. Its copolymers contribute to the desired properties of the coatings, including adhesion, durability, and resistance to environmental factors.
Used in Adhesives Industry:
In the adhesives industry, N-Pentyl Acrylate is utilized in the development of high-performance adhesives. Its copolymers enhance the adhesive's bonding strength, flexibility, and resistance to various substrates and environmental conditions.
Used in Textile Industry:
N-Pentyl Acrylate is employed in the textile industry for the production of durable and flexible fibers. Its copolymers can be used to create fibers with improved mechanical properties and resistance to wear and tear.
Used in Inks Industry:
In the inks industry, N-Pentyl Acrylate is used in the formulation of inkjet inks and other types of printing inks. Its copolymers contribute to the ink's performance, such as print quality, drying time, and resistance to smudging.
Used in Personal Care Industry:
N-Pentyl Acrylate is used in the personal care industry for the development of cosmetic and personal care products, such as creams, lotions, and hair care products. Its copolymers can improve the product's texture, spreadability, and stability.

InChI:InChI=1/C8H14O2/c1-3-5-6-7-10-8(9)4-2/h4H,2-3,5-7H2,1H3

Upstream product

• 71-41-0 pentan-1-ol 
• 292638-85-8 acrylic acid methyl ester 
• 79-10-7 acrylic acid 
• 814-68-6 acryloyl chloride 

Downstream Products

• 132876-36-9 1-(2-Pentyloxycarbonyl-ethyl)-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester 
• 1315276-25-5 C₂₂H₂₄N₂O₃ 
• 131751-34-3 (E)-3-phenylacrylic acid pentyl ester 
• 103-26-4 Methyl cinnamate 

Relevant academic research and scientific papers

Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment

Targeted protein degradation using small molecules is an intriguing strategy for drug development. The marine sesterterpene compound MHO7 had been reported to be a potential ERα degradation agent. In order to further improve its biological activity, two series of novel MHO7 derivatives with long side chains were designed and identified as novel selective estrogen receptor down-regulators (SERDs). The growth inhibition activity of the novel SERD compounds were significantly affected by the type and length of the side chain. Most of the derivatives were significantly more potent than MHO7 against both drug-sensitive and drug-resistant breast cancer cells. Among them, compound 16a, with IC50 values of 0.41 μM against MCF-7 cell lines and 9.6-fold stronger than MHO7, was the most potential molecule. A whole-genome transcriptomic analysis of MCF-7 cells revealed that the mechanism of 16a against MCF-7 cell was similar with that of MHO7. The estrogen signaling pathway was the most affected among the disturbed genes, but the ERα degradation activity of 16a was observed higher than that of MHO7. Other effects of 16a were confirmed similar with MHO7, which means that the basic mechanisms of the derivatives are the same with the ophiobolin backbone, i.e. the degradation of ERα is mediated via proteasome-mediated process, the induction of apoptosis and the cell cycle arrest at the G1 phase. Meanwhile, a decrease of mitochondrial membrane potential and an increase of cellular ROS were also detected. Based on these results, as a novel modified ophiobolin derived compound, 16a may warrant further exploitation as a promising SERD candidate agent for the treatment of breast cancer.

Acid- And base-switched palladium-catalyzed γ-C(sp3)-H alkylation and alkenylation of neopentylamine

The functionalization of remote unactivated C(sp3)-H and the reaction selectivity are among the core pursuits for transition-metal catalytic system development. Herein, we report Pd-catalyzed γ-C(sp3)-H-selective alkylation and alkenylation with removable 7-azaindole as a directing group. Acid and base were found to be the decisive regulators for the selective alkylation and alkenylation, respectively, on the same single substrate under otherwise the same reaction conditions. Various acrylates were compatible for the formation of C(sp3)-C(sp3) and C(sp3)-C(sp2) bonds. The alkenylation protocol could be further extended to acrylates with natural product units and α,β-unsaturated ketones. The preliminary synthetic manipulation of the alkylation and alkenylation products demonstrates the potential of this strategy for structurally diverse aliphatic chain extension and functionalization. Mechanistic experimental studies showed that the acidic and basic catalytic transformations shared the same six-membered dimer palladacycle.

Ε - propionic acid is amyl ester base - ε - caprolactone and its preparation method

The invention discloses an elpsilon-lactone perfume compound with a structure as described in the specification. The invention also discloses a preparation method for the elpsilon-lactone perfume compound. The preparation method comprises the following steps: with an acid compound and an alcohol compound as raw materials, subjecting the raw materials to esterification in an organic solvent under the action of an acid catalyst so as to obtain an amyl propionate compound; and with the amyl propionate compound and an alkene compound as raw materials carrying out addition and Baeyer-Villiger oxidation reaction under the action of an alkali catalyst and an acid catalyst so as to eventually obtain an elpsilon-amyl propionate-elpsilon-caprolactone compound. The novel elpsilon-lactone perfume compound with characteristic bouquet and fragrance of mellow and sweet rice wine is a novel research achievement of domestic and overseas research on elpsilon-lactone perfume compounds with characteristic fragrance.