2998-23-4

Basic information

• Product Name: N-PENTYL ACRYLATE
• Synonyms: 2-Propenoic acid,n-pentyl ester;2-propenoicacid,pentylester;Acrylic acid, pentyl ester;Amyl acrylate;Pentyl 2-propenoate;Pentyl acrylate;Pentylacrylate;N-AMYL ACRYLATE
• CAS NO: 2998-23-4
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.2
• EINECS: 221-074-2
• Product Categories: monomer
• Mol File: 2998-23-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 47-48°C 7mm
• Flash Point: 48.2°C
• Appearance: /
• Density: 0.893g/cm³
• Vapor Pressure: 1.54mmHg at 25°C
• Refractive Index: 1.423
• CAS DataBase Reference: N-PENTYL ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PENTYL ACRYLATE(2998-23-4)
• EPA Substance Registry System: N-PENTYL ACRYLATE(2998-23-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2998-23-4(Hazardous Substances Data)

Usage

General Description

N-Pentyl Acrylate is a chemical compound primarily used as an intermediate for organic synthesis and as a monomer for copolymerization. It possesses the chemical formula of C8H14O2 and falls under the category of acrylates. It has a mild or faint odour and appears as a clear, colorless liquid. N-Pentyl Acrylate is highly flammable and shows acute toxicity when inhaled, when it comes into contact with the skin, or if swallowed.?Furthermore, this chemical is harmful to aquatic life. Therefore, proper caution and safety measures should be followed while handling, storing, and disposing of N-Pentyl Acrylate to prevent exposure and environmental contamination.

InChI:InChI=1/C8H14O2/c1-3-5-6-7-10-8(9)4-2/h4H,2-3,5-7H2,1H3

Upstream product

• 71-41-0 pentan-1-ol 
• 814-68-6 acryloyl chloride 
• 79-10-7 acrylic acid 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 132876-36-9 1-(2-Pentyloxycarbonyl-ethyl)-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester 
• 1315276-25-5 C₂₂H₂₄N₂O₃ 
• 131751-34-3 (E)-3-phenylacrylic acid pentyl ester 
• 103-26-4 Methyl cinnamate 

Relevant articles and documents

Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment

Targeted protein degradation using small molecules is an intriguing strategy for drug development. The marine sesterterpene compound MHO7 had been reported to be a potential ERα degradation agent. In order to further improve its biological activity, two series of novel MHO7 derivatives with long side chains were designed and identified as novel selective estrogen receptor down-regulators (SERDs). The growth inhibition activity of the novel SERD compounds were significantly affected by the type and length of the side chain. Most of the derivatives were significantly more potent than MHO7 against both drug-sensitive and drug-resistant breast cancer cells. Among them, compound 16a, with IC50 values of 0.41 μM against MCF-7 cell lines and 9.6-fold stronger than MHO7, was the most potential molecule. A whole-genome transcriptomic analysis of MCF-7 cells revealed that the mechanism of 16a against MCF-7 cell was similar with that of MHO7. The estrogen signaling pathway was the most affected among the disturbed genes, but the ERα degradation activity of 16a was observed higher than that of MHO7. Other effects of 16a were confirmed similar with MHO7, which means that the basic mechanisms of the derivatives are the same with the ophiobolin backbone, i.e. the degradation of ERα is mediated via proteasome-mediated process, the induction of apoptosis and the cell cycle arrest at the G1 phase. Meanwhile, a decrease of mitochondrial membrane potential and an increase of cellular ROS were also detected. Based on these results, as a novel modified ophiobolin derived compound, 16a may warrant further exploitation as a promising SERD candidate agent for the treatment of breast cancer.

Ε - propionic acid is amyl ester base - ε - caprolactone and its preparation method

The invention discloses an elpsilon-lactone perfume compound with a structure as described in the specification. The invention also discloses a preparation method for the elpsilon-lactone perfume compound. The preparation method comprises the following steps: with an acid compound and an alcohol compound as raw materials, subjecting the raw materials to esterification in an organic solvent under the action of an acid catalyst so as to obtain an amyl propionate compound; and with the amyl propionate compound and an alkene compound as raw materials carrying out addition and Baeyer-Villiger oxidation reaction under the action of an alkali catalyst and an acid catalyst so as to eventually obtain an elpsilon-amyl propionate-elpsilon-caprolactone compound. The novel elpsilon-lactone perfume compound with characteristic bouquet and fragrance of mellow and sweet rice wine is a novel research achievement of domestic and overseas research on elpsilon-lactone perfume compounds with characteristic fragrance.