2999-10-2

Basic information

• Product Name: 1-Butanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[3-methyl-
• Synonyms: 2,4-diisovalerylphloroglucinol;2,4-isovalerylphloroglucinol;2',4',6'-Trihydroxy-3'-isovaleryl-isovalerophenon;diisovaleryl phloroglucinol;1,3-di-(3-methyl-butanoyl)-2,4,6-trihydroxybenzene
• CAS NO: 2999-10-2
• Molecular Formula: C16H22O5
• Molecular Weight: 294.348
• Mol File: 2999-10-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[3-methyl-(2999-10-2)
• EPA Substance Registry System: 1-Butanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[3-methyl-(2999-10-2)

Safety Data

• Hazardous Substances Data: 2999-10-2(Hazardous Substances Data)

Usage

General Description

1-Butanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[3-methyl- is a chemical compound that consists of a butanone (also known as methyl ethyl ketone) molecule attached to a phenylene group with three hydroxy groups at positions 2, 4, and 6. 1-Butanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[3-methyl- is commonly used as a solvent in various industries and can also be found in some household products. The presence of the phenylene group with hydroxy groups gives this compound potential antioxidant and antimicrobial properties, making it useful in certain applications. However, it is important to handle this chemical with care and follow proper safety precautions due to its potential health hazards.

Upstream product

• 503-74-2 3-methylbutyric acid 
• 108-73-6 3,5-dihydroxyphenol 
• 108-12-3 isopentanoyl chloride 
• 26103-97-9 phloroisovalerophenone 

Downstream Products

• 145747-74-6 3,5-Dihydroxy-2,6-bis-(3-methyl-butyryl)-4,4-dipentyl-cyclohexa-2,5-dienone 
• 1224583-54-3 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)-pyridin-2-yl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-55-4 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)-furan-2-yl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-45-2 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)phenylethylmethyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-56-5 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)-quinolin-4-yl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-50-9 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)-4-benzyloxyphenyl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-57-6 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)-3,4-methylenedioxyphenyl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-47-4 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)phenylmethyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 1224583-48-5 1-[3-isopentanoyl-5-[(3,5-diisopentanoyl-2,4,6-trihydroxyphenyl)-4-hydroxyphenyl-methyl]-2,4,6-trihydroxyphenyl]-3-methylbutan-1-one 
• 69298-83-5 1,1′-(4,6-dihydroxy-5,5-dimethyl-2-oxocyclohexa-3,6-diene-1,3-diyl)bis(3-methylbutan-1-one) 
• 1400992-06-4 1-(2,4,6-trihydroxy-3,5-diisovaleryl-benzyl)azepan-2-one 
• 1384189-37-0 6,8-di-(3-methyl-butyryl)-5,7-dihydroxy-4'-methyl-flavan 
• 1384189-34-7 6,8-di-(3-methylbutyryl)-5,7-dihydroxyflavan 
• 1367716-00-4 C₄₁H₄₆F₆O₁₀ 

Relevant articles and documents

Inhibitors of skin-tumor promotion. VIII. Inhibitory effects of euglobals and their related compounds on Epstein-Barr virus activation. (1)

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Diacylphloroglucinol derivatives as antioxidant agents: green synthesis, optimisation, in?vitro, and in silico evaluation

Several derivatives of diacylphloroglucinol (3a–3c and 5a–5b) as an analogue of natural product compound 2,4-diacetylphloroglucinol 3a, were successfully synthesised in an excellent yield via a greener Friedel–Craft acylation using methanesulfonic acid (MSA) as a catalyst under an ultrasound-assisted condition. Operational simplicity, excellent yield, expedient metal-free synthesis, energy-efficient and mild reaction conditions are the outstanding advantages in this procedure. A scaled-up reaction also revealed the practical suitability of this newly developed procedure. The effects of several process variables on 3a were carefully accomplished using response surface methodology (RSM). Moreover, the green credentials of the present protocol have been assessed using several established green metrics and compared to relevant procedures. Along with the monomers, dimeric diacylphloroglucinols (6a–6e) were also synthesised and their in?vitro antioxidant activity of these species were carried out. Furthermore, drug-likeness, density functional theory (DFT), and molecular docking studies were also established.

Highly efficient and green synthesis of diacylphloroglucinol over treated natural zeolite mordenite and the optimization using response surface method (RSM)

Herein, we report a greener and highly efficient route for the Friedel-Craft acylation of phloroglucinol over Indonesian treated natural zeolite mordenite (nHZMOR) catalyst to provide value-added diacylphloroglucinol derivatives under solvent-free conditi