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30007-59-1

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30007-59-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 30007-59-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,0,0 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 30007-59:
(7*3)+(6*0)+(5*0)+(4*0)+(3*7)+(2*5)+(1*9)=61
61 % 10 = 1
So 30007-59-1 is a valid CAS Registry Number.

30007-59-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(3-amino-1,4-dioxonaphthalen-2-yl)-2-chloroacetamide

1.2 Other means of identification

Product number -
Other names Acetamide,N-(3-amino-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-2-chloro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:30007-59-1 SDS

30007-59-1Downstream Products

30007-59-1Relevant articles and documents

Synthesis, biological properties, and acid dissociation constant of novel naphthoquinone–triazole hybrids

Nural, Yahya,Ozdemir, Sadin,Doluca, Osman,Demir, Bunyamin,Yalcin, Mustafa Serkan,Atabey, Hasan,Kanat, Beyza,Erat, Selma,Sari, Hayati,Seferoglu, Zeynel

, (2020)

A series of novel 1,4-naphthoquinone–triazole hybrids, N-(3-amino-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-2-(4-R-1H-1,2,3-triazol-1-yl)acetamide, was synthesized by click chemistry in the presence of sodium ascorbate and copper(II) sulfate pentahydrate in 81–94% yield. Various biological properties of the synthesized compounds including DNA binding/cleavage, antioxidant, antibacterial and antifungal properties were evaluated. The DNA binding study was performed using dsDNA and G-quadruplex DNA. All of the compounds showed fluorescence increase in the presence of DNA, regardless of the structure. Up to 2.9 and 2.5 times fluorescence increase upon incubation with double stranded or G-quadruplex DNA was detected for 5f and 5g, respectively. The docking studies performed on dsDNA and G-quadruplex structures suggested compounds’ mode of interactions were populated around the grooves. All of the compounds showed excellent DNA cleavage activity and 5e was almost degraded the plasmid DNA. The highest radical scavenging activity was obtained as 89.9% at 200 mg/L with 5d. However, the highest ferrous chelating activity was obtained as 68.1% at 200 mg/L with 5g. The compounds exhibited antimicrobial activity against Bacillus cereus, Legionella pneumophila subsp. pneumophila, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Enterococcus hirae as bacteria strains and Candida albicans and Candida tropicalis as microfungus strains. The compounds exhibited antibacterial and antifungal activity in the range of 4–128 μg/mL and 16–128 μg/mL, respectively. The best antimicrobial activity was obtained with 5d and 5e with a MIC value of 4 μg/mL against Enterococcus hirae. The acid dissociation constants (pKa) were determined potentiometrically in 20% (v/v) dimethyl sulfoxide-water hydro-organic solvent at an ionic background of 0.1 mol/L of NaCl, at 25 ± 0.1 °C. Five pKa values were obtained for each ligand.

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