30034-41-4Relevant academic research and scientific papers
A concise regiospecific synthesis of 8,8-dimethyl-2H, 8H-pyrano [6, 5- h]quinolin-2-one and related compounds
Yang, Zheng-Yu,Xia, Yi,Xia, Peng,Brossi, Arnold,Lee, Kuo-Hsiung
, p. 4505 - 4506 (1999)
An efficient method for the regiospecific synthesis of 8,8-dimethyl- 2H,8H-pyrano[6,5-h]quinolin-2-one and related compounds via a Claisen rearrangement is described.
QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER
-
Page/Page column 78; 80, (2020/10/09)
The present invention relates to compounds of the general formula (I): (I), wherein V, W, M, R, R and Y have the designations cited below, or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof, and to processes for the preparation of compounds of the general formula (I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof. The invention also relates to compounds of the general formula(I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof for use as a medicament. Further, the invention relates to compounds of the general formula (I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof for use in the treatment of cancer. Moreover, the invention relates to compounds of the general formula(I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof for treating cancer in simultaneous, alternating or subsequent combination with another cancer therapy.
Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
-
, (2008/06/13)
Compounds having the formula I: STR1 are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
