300345-76-0

Usage

Uses

Used in Pharmaceutical Industry:
(1S,2S)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+% is utilized as a reagent in the synthesis of pharmaceuticals, leveraging its chiral properties to produce enantiomerically pure compounds essential for drug development. (1S,2S)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+%'s ability to serve as a chiral ligand or catalyst in asymmetric reactions ensures the production of the desired enantiomer, which is crucial for the efficacy and safety of many medications.
Used in Organic Synthesis:
In the realm of organic synthesis, (1S,2S)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+% is employed as a key intermediate for the preparation of various chiral compounds. Its high purity and specific stereochemistry make it suitable for reactions that require precise control over the spatial arrangement of atoms, contributing to the synthesis of complex organic molecules with specific biological activities.
Used in Catalyst Production:
(1S,2S)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+% is also used in the production of chiral catalysts, which are vital in asymmetric catalysis. These catalysts are employed to accelerate chemical reactions with a high degree of enantioselectivity, ensuring that the desired enantiomer is preferentially formed. This is particularly important in the synthesis of biologically active compounds, where the stereochemistry of the molecule can significantly impact its activity.
Used in Research and Development:
In academic and industrial research settings, (1S,2S)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+% serves as a valuable tool for exploring new reaction pathways and developing innovative synthetic methods. Its high purity and well-defined stereochemistry make it an ideal candidate for studying the mechanisms of asymmetric reactions and for testing new catalytic systems.

Upstream product

• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1295509-72-6 C₃₆H₄₁N₅O₃S₂ 
• 1352614-15-3 N-((1S,2S)-2-(3-((1R)-(6-methoxyquinolin-4-yl)((2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)-1,2-diphenylethyl)methanesulfonamide 
• 1353719-77-3 N-((1S,2S)-2-(3-((S)-3,3-dimethyl-1-(pyrrolidin-1-yl)butan-2-yl)thioureido)-1,2-diphenylethyl)methanesulfonamide 
• 1360897-47-7 N-((1S,2S)-1,2-diphenyl-2-(2-(tetrahydro-2H-pyran-2-yloxy)ethylamino)ethyl)methanesulfonamide 
• 1360897-48-8 N-((1S,2S)-2-(2-hydroxyethylamino)-1,2-diphenylethyl)methanesulfonamide 
• 1245811-48-6 tethered (S,S)-MsDPEN 
• 1404469-38-0 N-((1S,2S)-2-(4-(4-methylcyclohexa-1,4-dienyl)butylamino)-1,2-diphenylethyl)methanesulfonamide hydrochloride 
• 1404469-40-4 N-((1S,2S)-2-(4-(5-methylcyclohexa-1,4-dienyl)butylamino)-1,2-diphenylethyl)methanesulfonamide hydrochloride 

Relevant academic research and scientific papers

Catalytic asymmetric Michael addition with curcumin derivative

Catalytic asymmetric Michael additions with curcumin derivatives were achieved by a new series of tertiary amine-thiourea organocatalysts to afford the Michael adducts in high yields and excellent enantioselectivities.

Ir(III) complexes of diamine ligands for asymmetric ketone hydrogenation

The use of a combination of IrCl3 with a series of ligands derived from the C2-symmetric diamine diphenylethanediamine (DPEN) forms a catalyst capable of the asymmetric hydrogenation of ketones in up to 85% ee.

METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES

The present invention is directed to processes for the preparation of a tricyclic amino-alcohol derivative useful for treating and preventing diabetes, obesity, hyperlipidemia and the like, which compound is represented by the formula (1): wherein R1 represents a lower alkyl group or a benzyl group; *1 represents an asymmetric carbon atom; R2 represents a hydrogen atom, a halogen atom or a hydroxyl group; and A represents one of the following groups: wherein X represents NH, O or S; R5 represents a hydrogen atom, a hydroxyl group, an amino group or an acetylamino group; and *2 represents an asymmetric carbon atom when R5 is not a hydrogen atom. The processes of the present invention proceed via azide derivatives and are convenient, practical preparing processes with low cost which comprise a small number of steps with good industrial work efficiency.