300355-18-4

Basic information

• Product Name: METHYL 2-(4-(METHYLSULFONYL)PHENYL)ACETATE
• Synonyms: METHYL 2-(4-(METHYLSULFONYL)PHENYL)ACETATE;(4-methanesulfonyl-phenyl)-acetic acid methyl ester
• CAS NO: 300355-18-4
• Molecular Formula: C₁₀H₁₂O₄S
• Molecular Weight: 228.26488
• Mol File: 300355-18-4.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 2-(4-(METHYLSULFONYL)PHENYL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-(4-(METHYLSULFONYL)PHENYL)ACETATE(300355-18-4)
• EPA Substance Registry System: METHYL 2-(4-(METHYLSULFONYL)PHENYL)ACETATE(300355-18-4)

Safety Data

• Hazardous Substances Data: 300355-18-4(Hazardous Substances Data)

Usage

General Description

Methyl 2-(4-(methylsulfonyl)phenyl)acetate is a chemical compound with the molecular formula C11H14O4S. It is an ester, which means it is derived from an acid in which at least one -OH (hydroxyl) group is replaced by an -O-alkyl group. This particular ester contains a phenyl ring with a methylsulfonyl group attached to it. Methyl 2-(4-(methylsulfonyl)phenyl)acetate is commonly used as a flavoring agent in the food industry and as a fragrance in the perfume industry. It may also have other industrial or pharmaceutical applications due to its aromatic and functional group properties.

Upstream product

• 90536-66-6 4-(methylsulfonyl)phenylacetic acid 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 
• 20277-69-4 sodium methansulfinate 
• 16188-55-9 2-(4-(methylthio)phenyl)acetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67-56-1 methanol 
• 1360789-02-1 2-(4-(methylsulfonyl)phenyl)-1-(2,2,6,6-tetramethylpiperidin-1-yl)ethanone 
• 70290-37-8 (4-methylsulfanyl-phenyl)-acetic acid methyl ester 

Downstream Products

• 557798-35-3 bromo-(4-methylsulfonyl-phenyl)-acetic acid methyl ester 
• 189954-96-9 3-(Cyclopropylmethoxy)-5.5-dimethyl-4-(4-(methylsulfonyl)phenyl)-5H-furan-2-one 
• 428508-13-8 2-(4-(methylsulfonyl)phenyl)acetohydrazide 
• 1052721-38-6 {5-chloro-2-[2-(2,4-difluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-propionylamino]-thiazol-4-yl}-acetic acid 
• 1052722-23-2 {5-chloro-2-[2-(2,4-difluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-propionylamino]-thiazol-4-yl}-acetic acid methyl ester 
• 1052721-10-4 2-(2,4-difluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-N-thiazol-2-yl-propionamide 
• 1052722-43-6 2-(2,4-difluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-propionic acid methyl ester 
• 1052722-22-1 2-(2,4-difluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-propionic acid 
• 1052722-21-0 2-bromo-2-(4-methanesulfonyl-phenyl)-propionic acid methyl ester 
• 90536-66-6 4-(methylsulfonyl)phenylacetic acid 
• 1380646-54-7 acetic acid 5-[3-(3-fluorophenyl)-2-(4-methanesulfonylphenyl)-propionylamino]-pyrazin-2-ylmethyl ester 
• 1380646-47-8 N-[6-(tert-butyl-dimethyl-silanyloxymethyl)-benzooxazol-2-yl]-3-(4-fluorophenyl)-2-(4-methanesulfonylphenyl)-propionamide 
• 1380646-64-9 5-[3-(4-fluoro-phenyl)-2-(4-methanesulfonylphenyl)propionylamino]-pyrazine-2-carboxylic acid methyl ester 
• 1380646-32-1 (S)-3-(4-Fluoro-phenyl)-N-(5-hydroxymethyl-pyrazin-2-yl)-2-(4-methanesulfonyl-phenyl)-propionamide 

Relevant articles and documents

HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE

Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being described in the specifications. The compound represented by formula (I) can be used as the ligand in the copper catalyzed coupling reaction of the aryl halogeno substitute, and is used or catalyzing the coupling reaction for forming the aryl halogeno substitute having C—N, C—O, C—S and other bonds.

FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS

The present invention provides fused thiophene and thiazole derivatives of formula (I), which may be therapeutically useful, more particularly as RORγ modulators; in which R1, R2, R3, R4, R5, R6, R7, X1, X2, L, m, n and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in disease(s) or disorder(s) where there is an advantage in modulating RORγ receptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the fused thiophene and thiazole derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

TRISUBSTITUTED HETEROCYCLIC DERIVATIVES AS ROR GAMMA MODULATORS

The present invention provides trisubstituted heterocyclic derivatives of formula (I), which may be therapeutically useful, more particularly as RORγ modulators; (I) in which R1, R2, R3, Ra, X, L, m and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder where there is an advantage in modulating RORγ receptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the trisubstituted heterocyclic derivatives of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient therefor.