30046-68-5Relevant academic research and scientific papers
Photocatalyzed ortho-Alkylation of Pyridine N-Oxides through Alkene Cleavage
Zhou, Wang,Miura, Tomoya,Murakami, Masahiro
supporting information, p. 5139 - 5142 (2018/05/30)
A photocatalyzed reaction of pyridine N-oxides with alkenes gives ortho-alkylated pyridines with cleavage of the carbon–carbon double bond. Benzyl and secondary alkyl groups are incorporated at the ortho position of pyridines in one pot.
Palladium-catalyzed decarboxylative couplings of 2-(2-Azaaryl)acetates with aryl halides and triflates
Shang, Rui,Yang, Zhi-Wei,Wang, Yan,Zhang, Song-Lin,Liu, Lei
supporting information; experimental part, p. 14391 - 14393 (2010/12/19)
Pd-catalyzed decarboxylative cross-couplings of 2-(2-azaaryl)acetates with aryl halides and triflates have been discovered. This reaction is potentially useful for the synthesis of some functionalized pyridines, quinolines, pyrazines, benzoxazoles, and benzothiazoles. Theoretical analysis shows that the nitrogen atom at the 2-position of the heteroaromatics directly coordinates to Pd(II) in the decarboxylation transition state.
A New Route for the Synthesis of 2-Amino-biphenyls Involving Enamine Rearrangement of Pyridinium Salts
Fadda, A. A.,El-Morsy, S. S.
, p. 361 - 363 (2007/10/02)
2-Benzyl-1-methylpyridinium iodides (IIa-c) undergo ring opening and recyclization reactions when heated with aq. sodium hydroxide to give 2-methylaminobiphenyls (IIIa-c).The effect of aq. alkylamine and alkylammonium sulphite solution on this type of reaction has also been studied.
PREPARATION OF PYRIMIDINES AND PYRIDINES FROM ALKYL KETONES AND NITRILES IN PRESENCE OF PHOSPHORYL CHLORIDE
Zielinski, Wojciech
, p. 1639 - 1644 (2007/10/02)
The reaction of alkyl ketones with nitriles in the presence of POCl3 has been examined.It has been found that N-vinylimidoyl dichlorophosphates initially formed react further with excess nitriles or ketones to afford pyrimidine or pyridine derivatives, respectively.
RECYCLIZATION OF 2-BENZYLPYRIDINIUM SALTS TO 2-AMINOBIPHENYLS
Kost, A. N.,Fadda, A.,Sagitullin, R. S.,Gromov, S. P.,Petrunina, T. I.,Sharbatyan, P. A.
, p. 970 - 976 (2007/10/02)
Under the influence of aqueous solutions of alkylammonium sulfites, substituted 2-benzylpyridinium salts undergo rearrangement to 2-aminobiphenyls.The competitive processes that occur during rearrangement of the 2-benzylpyridinium salts were studied.
