30060-24-3Relevant academic research and scientific papers
Triazolo derivatives of dibenzodiazepines as potential C. N. S. active drug
Joshi, Jyoti U.,Joshi, Bidya S.,Joshi
, p. 141 - 145 (2009)
The synthesis of a number of substituted triazolo derivatives of Dibenzodiazepines are reported. The medicinal properties were evaluated through various pharmacological assessments applied on albino mice of either sex taking clozapine as standard drug. A triazolo derivatives having substitution at 8-positions Dibenzodiazepines was found to have for better CNS depressant activity properties as compared to the basic Dibenzodiazepines moeity and among other 8-subsituted derivatives amino substitution exhibited 70 - 80 % antiepileptic properties.
