Heterocyclic Communications p. 141 - 145 (2009)
Update date:2022-08-05
Topics:
Joshi, Jyoti U.
Joshi, Bidya S.
Joshi
The synthesis of a number of substituted triazolo derivatives of Dibenzodiazepines are reported. The medicinal properties were evaluated through various pharmacological assessments applied on albino mice of either sex taking clozapine as standard drug. A triazolo derivatives having substitution at 8-positions Dibenzodiazepines was found to have for better CNS depressant activity properties as compared to the basic Dibenzodiazepines moeity and among other 8-subsituted derivatives amino substitution exhibited 70 - 80 % antiepileptic properties.
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