30062-44-3

Basic information

• Product Name: 5-ALLYLSULFANYL-[1,3,4]THIADIAZOL-2-YLAMINE
• Synonyms: 5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-amine
• CAS NO: 30062-44-3
• Molecular Formula: C₅H₇N₃S₂
• Molecular Weight: 173.26
• Mol File: 30062-44-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 316.1°Cat760mmHg
• Flash Point: 145°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 0.000419mmHg at 25°C
• Refractive Index: 1.635
• PKA: 2.33±0.10(Predicted)
• CAS DataBase Reference: 5-ALLYLSULFANYL-[1,3,4]THIADIAZOL-2-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ALLYLSULFANYL-[1,3,4]THIADIAZOL-2-YLAMINE(30062-44-3)
• EPA Substance Registry System: 5-ALLYLSULFANYL-[1,3,4]THIADIAZOL-2-YLAMINE(30062-44-3)

Safety Data

• Hazardous Substances Data: 30062-44-3(Hazardous Substances Data)

Usage

General Description

5-Allylsulfanyl-[1,3,4]thiadiazol-2-ylamine is a chemical compound with the molecular formula C6H8N4S2. It consists of a thiadiazole ring with an allyl group and an amine group attached to it. 5-ALLYLSULFANYL-[1,3,4]THIADIAZOL-2-YLAMINE is of interest due to its potential biological and pharmaceutical applications. It has been studied for its antimicrobial, antifungal, and anti-inflammatory properties. Additionally, derivatives of 5-Allylsulfanyl-[1,3,4]thiadiazol-2-ylamine have been investigated for their potential as anti-tumor and anti-cancer agents. The compound's unique structure and potential therapeutic properties make it a subject of interest for further research and development.

InChI:InChI=1/C5H7N3S2/c1-2-3-9-5-8-7-4(6)10-5/h2H,1,3H2,(H2,6,7)

Upstream product

• 2349-67-9 2-Amino-5-mercapto-1,3,4-thiadiazole 
• 106-95-6 allyl bromide 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 54508-95-1 (5-allylsulfanyl-[1,3,4]thiadiazol-2-yl)-dithiocarbamic acid benzyl ester 
• 70863-54-6 2-allylsulfanyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazole 
• 69395-67-1 2-allylsulfanyl-6-benzyl-[1,3,4]thiadiazolo[3,2-a]pyrimidine-5,7-dione 
• 69395-64-8 2-allylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidine-5,7-dione 

Relevant articles and documents

Crystal structure of an AgClO4 π complex with 2-amino-5-allylthio-1,3,4-thiadiazole of the composition [Ag(C5H7N3S2)(ClO4)]

By interaction of AgClO4 with 2-amino-5-allylthio-1,3,4-thiadiazole (Aаtd) in the ethanol solution, a new [Ag(Aаtd)(ClO4)] π complex is obtained. It is studied by single crystal X-ray diffraction.

Design and development of 1,3,4-thiadiazole based potent new nano-fungicides

Being the important organic reaction intermediates and biological scaffolds, a series of 2-alkyl/aralkyl/heterocyclyl sulfanyl-5-amino/methyl-1,3,4-thiadiazoles have been synthesized by suitable synthetic route and characterized by analytical and spectral data. The evaluation of these compounds for their bioefficacy against two phyto-pathogenic fungi revealed their fungicidal potency against Rhizoctonia bataticola (ED50 values, 3.9–300.4 μg/mL) and Rhizoctonia solani (ED50 values, 4.2–228.5 μg/mL). To further augment their fungicidal efficacy, the potent five fungicidal compounds were nano-sized. The protocol for preparing 1,3,4-thiadiazole based nano-fungicide employing polyethylene glycol was developed and standardized. Characterization of nano-forms of 1,3,4-thiadiazole derivatives by particle size analyzer and electron microscopy (TEM) techniques confirmed the 100 nm average particle sizes of all nano-fungicides. The 2–4 times higher fungicidal activity was observed with nano-forms than the corresponding conventional sized 1,3,4-thiadiazole derivatives against phytopathogenic fungi, namely, Rhizoctonia solani and R. bataticola.