300658-41-7Relevant academic research and scientific papers
Synthesis of BMS-309403-related compounds, including [14C]BMS- 309403, a radioligand for adipocyte fatty acid binding protein
Okada, Toshihiko,Hiromura, Makoto,Otsuka, Masato,Enomoto, Shuichi,Miyachi, Hiroyuki
, p. 164 - 168 (2012/02/16)
Adipocyte fatty acid binding protein (A-FABP; FABP4), which is predominantly expressed in macrophages and adipose tissue, regulates fatty acid storage and lipolysis, and is also an important mediator of inflammation. Here, we report a synthesis of 14
Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP)
Sulsky, Richard,Magnin, David R.,Huang, Yanting,Simpkins, Ligaya,Taunk, Prakash,Patel, Manorama,Zhu, Yeheng,Stouch, Terry R.,Bassolino-Klimas, Donna,Parker, Rex,Harrity, Thomas,Stoffel, Robert,Taylor, David S.,Lavoie, Thomas B.,Kish, Kevin,Jacobson, Bruce L.,Sheriff, Steven,Adam, Leonard P.,Ewing, William R.,Robl, Jeffrey A.
, p. 3511 - 3515 (2008/02/09)
Herein we report the first disclosure of biphenyl azoles that are nanomolar binders of adipocyte fatty acid binding protein (aFABP or aP2) with up to thousand-fold selectivity against muscle fatty acid binding protein and epidermal fatty acid binding prot
