300662-53-7

Basic information

• Product Name: Cu(II)(1,3-bis(2-pyridylimino)isoindolinate)(O-benzoylsalicylic acid)
• Synonyms: Cu(II)(1,3-bis(2-pyridylimino)isoindolinate)(O-benzoylsalicylic acid)
• CAS NO: 300662-53-7
• Molecular Weight: 603.096
• Mol File: 300662-53-7.mol

Chemical Properties

• CAS DataBase Reference: Cu(II)(1,3-bis(2-pyridylimino)isoindolinate)(O-benzoylsalicylic acid)(CAS DataBase Reference)
• NIST Chemistry Reference: Cu(II)(1,3-bis(2-pyridylimino)isoindolinate)(O-benzoylsalicylic acid)(300662-53-7)
• EPA Substance Registry System: Cu(II)(1,3-bis(2-pyridylimino)isoindolinate)(O-benzoylsalicylic acid)(300662-53-7)

Safety Data

• Hazardous Substances Data: 300662-53-7(Hazardous Substances Data)

Upstream product

• 577-85-5 3-hydroxyflavone 
• 14526-01-3 1,3-bis-(2-pyridylimino)isoindoline 
• 300662-51-5 (Cu(II)(flavonolate)(1,3-bis(2-pyridylimino)isoindolinate)) 
• 300662-50-4 (Cu(I)(flavonolate)(1,3-bis(2-pyridylimino)isoindoline)) 
• 4578-66-9 o-benzoyloxybenzoic acid 
• 75732-01-3 mesitylcopper(I) 

Relevant articles and documents

Preparation and oxygenation of (flavonolato)copper isoindoline complexes with relevance to quercetin dioxygenase

Mesitylcopper reacts with flavonol (flaH) in the presence of 1,3-bis(2-pyridylimino)isoindoline (indH) to yield the diamagnetic complex Cu(I)(fla)(indH), which on reaction with molecular oxygen undergoes oxidative splitting of the C2 - C3 bond of the pyranone ring of the flavonolate ligand to give Cu(I)(indH)(O-bs) (O-bs = O-benzoylsalicylate) (orthorhombic, P1, a = 8.048(7) A, b = 8.969(9) A, c = 19.240(2) A, α = 85.69°, β = 80.24(7)°, γ = 77.87(7)°, V = 1337(2) A3, Z = 2) and carbon monoxide. The reaction of [Cu(I)(CH3CN)4]ClO4, flaH, and indH with dioxygen at room temperature affords the paramagnetic complex [Cu(II)(fla)(indH)]ClO4 (υ = 2.10 υ(B)), and after elimination of HClO4, Cu(II)(fla)(ind) (orthorhombic, P(bca,) a = 8.888(2) A, b = 19.169(7) A, c = 33.614(10) A, α = β = γ = 90°, V = 5727(3) A3, Z = 8) with υ = 1.86 υ(B) is formed. The latter undergoes cleavage of the pyranone ring on oxygenation at 80 °C to give Cu(II)(ind)(O-bs) (υ = 1.87 υ(B), v(CO) = 1742 cm-1, and v(CO2) = 1581, 1387 cm-1) and carbon monoxide. Cu(II)(fla)(ind) and [Cu(II)(fla)(indH)]ClO4 serve as good catalysts for the oxygenation of flavonol to O-benzoylsalicylic acid.