30087-33-3Relevant academic research and scientific papers
Development of photo-controllable hydrogen sulfide donor applicable in live cells
Fukushima, Naoki,Ieda, Naoya,Kawaguchi, Mitsuyasu,Sasakura, Kiyoshi,Nagano, Tetsuo,Hanaoka, Kenjiro,Miyata, Naoki,Nakagawa, Hidehiko
, p. 175 - 178 (2015)
Hydrogen sulfide (H2S) has multiple physiological roles, for example, in vasodilation and inflammation. It is a highly reactive gas under ambient conditions, so controllable H2S donors are required for studying its biological functions. Here, we describe the design, synthesis and application of a H2S donor (SPD-2) that utilizes xanthone photochemistry to control H2S release. H2S generation from SPD-2 was completely dependent on UVA-irradiation (325-385 nm), as confirmed by methylene blue assay and by the use of a H2S-selective fluorescent probe. SPD-2 was confirmed to provide controlled H2S delivery in live cells, and should be suitable for various biological applications.
Photolabile protecting groups based on the singlet state photodecarboxylation of xanthone acetic acid
Blake, Jessie A.,Lukeman, Matthew,Scaiano, Juan C.
supporting information; experimental part, p. 4127 - 4135 (2009/09/04)
A new photolabile protecting group (PPG) for carboxylic acids and amineshas been developed based on the rapid singlet state photodecarboxylatio n of xanthone acetic acids with several features that are superior to many other systems. We demonstrate that t
