30091-24-8

Usage

Uses

Used in Pharmaceutical Industry:
2-(ethylamino)benzonitrile is used as a chemical intermediate for the synthesis of various organic compounds, particularly in the development of pharmaceuticals that can target a range of health conditions due to its antimicrobial, antitumor, and antioxidant properties.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 2-(ethylamino)benzonitrile serves as an intermediate in the synthesis of compounds designed to protect crops and enhance agricultural productivity, leveraging its antimicrobial properties to combat pests and diseases.
Used in Dye and Pigment Production:
2-(ethylamino)benzonitrile is utilized as a building block in the creation of dyes and pigments, contributing to the development of a diverse palette of colorants for various applications, from textiles to printing inks, due to its chemical structure that allows for the production of a wide range of colors.
Used in Specialty Chemicals:
2-(ethylamino)benzonitrile also plays a role in the production of specialty chemicals, where its unique properties can be harnessed for specific industrial applications, such as in the formulation of high-performance materials or in advanced chemical processes.

Upstream product

• 75-03-6 ethyl iodide 
• 1885-29-6 anthranilic acid nitrile 
• 394-47-8 2-fluorobenzonitrile 
• 612-64-6 N-ethyl-N-nitrosoaniline 
• 55305-43-6 N-cyano-N-phenyl-p-toluenesulfonamide 
• 802294-64-0 propionic acid 

Downstream Products

• 125160-57-8 3-Allyl-1-(2-cyano-phenyl)-1-ethyl-urea 
• 61453-53-0 2-methyl-4-phenylquinazoline 

Relevant academic research and scientific papers

Visible-Light-Enabled Direct Decarboxylative N-Alkylation

The development of efficient and selective C?N bond-forming reactions from abundant feedstock chemicals remains a central theme in organic chemistry owing to the key roles of amines in synthesis, drug discovery, and materials science. Herein, we present a dual catalytic system for the N-alkylation of diverse aromatic carbocyclic and heterocyclic amines directly with carboxylic acids, by-passing their preactivation as redox-active esters. The reaction, which is enabled by visible-light-driven, acridine-catalyzed decarboxylation, provides access to N-alkylated secondary and tertiary anilines and N-heterocycles. Additional examples, including double alkylation, the installation of metabolically robust deuterated methyl groups, and tandem ring formation, further demonstrate the potential of the direct decarboxylative alkylation (DDA) reaction.

Rhodium(III)-Catalyzed Direct Cyanation of Aromatic C-H Bond to Form 2-(Alkylamino)benzonitriles Using N-Nitroso As Directing Group

2-(Alkylamino)benzonitriles were synthesized via a rhodium-catalyzed cyanation on the aryl C-H bond and subsequent denitrosation of N-nitrosoarylamines using a removable nitroso as the directing group, in which N-cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS) was used as the "CN" source. Various substituents on the aryl ring and amino group of N-nitrosoarylamines tolerated the reaction, and the corresponding products were achieved in moderate to good yields.

Method of inhibiting neoplastic cells with imidazoquinazoline derivatives

A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to imidazoquinazoline derivatives.

Imidazoquinazoline derivatives

PCT No. PCT/JP97/03023 Sec. 371 Date Apr. 27, 1998 Sec. 102(e) Date Apr. 27, 1998 PCT Filed Aug. 29, 1997 PCT Pub. No. WO98/08848 PCT Pub. Date Mar. 5, 1998Imidazoquinoline derivatives of the formula (wherein X may be O or S) provide selective cyclic guanosine 3',5' monophosphate (cGMP)-specific phosphodiesterase (PDE) inhibitory activity. The compounds are useful for treating or ameliorating cardiovascular disease such as thrombosis, angina pectoris, hypertension, heart failure and arterial sclerosis, as well as asthma, impotence and the like.

Cytomegalovirus inhibiting compounds

The present invention relates to heterocyclic compounds having antiviral activity. In particular, compounds of formula (I): wherein B, W, X, Y, R1, R2, R3, R4 and n are as defined herein, are useful in the thera